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5

Insight into advances in diagnosis of Barrett’s esophagus

Barrett’s esophagus has been established as a pre-cancerous condition that increases an individual’s risk of developing esophageal cancer, and so regular monitoring people with Barrett’s esophagus can help improve the survival rates of those who develop cancer. However, diagnosis is usually by endoscopy, which is invasive, unpleasant and resource-intensive. CLI caught up with Charlene Tang […]

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Therapeutic drug monitoring of favipiravir, a potential COVID-19 drug candidate

The COVID-19 outbreak caused by severe acute respiratory syndrome virus 2 (SARS-CoV-2) that was declared a pandemic in March 2020 has resulted in a the development of diagnostic tests and vaccines at an unprecedented speed. The development of de novo therapeutics, though, takes considerably longer, which is where the repurposing of existing drugs is being […]

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How the COVID-19 response was informed by – and informs – our battle against other global health crises

The COVID-19 pandemic has reinforced the critical importance of diagnosis and access to these services, both at the individual and at a population level. The pandemic has also impacted the delivery of diagnostics and care for other medical conditions, such as HIV/AIDS, but similarly, lessons learned with COVID-19 can also be applied to improve diagnostic […]

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Colorimetric histology: benefits, opportunities and future directions

Despite rapid advances in the areas of genomics and digital image analysis, cancer diagnosis remains largely reliant on tissue/cellular morphological assessment by an expert pathologist. Here, we summarize a newly developed approach to histology, based on a plasmon-induced colour change which provides instant, label-free visualization (or contrast) of cancer cells, distinguishing them from other cells […]