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1

A microscopic look at aneurysm repair

Hitting a pothole on the road in just the wrong way might create a bulge on the tire, a weakened spot that will almost certainly lead to an eventual flat tire. But what if that tire could immediately begin reknitting its rubber, reinforcing the bulge and preventing it from bursting?

2

New immunotherapy target discovered for malignant brain tumour

Scientists say they have discovered a potential new target for immunotherapy of malignant brain tumours, which so far have resisted the ground-breaking cancer treatment based on harnessing the body’s immune system. The discovery, reported in the journal CELL, emerged from laboratory experiments and has no immediate implications for treating patients.

5

Liquid biopsy for colorectal cancer could guide therapy for tumours

A new study from Washington University School of Medicine in St. Louis demonstrates that a liquid biopsy examining blood or urine can help gauge the effectiveness of therapy for colorectal cancer that has just begun to spread beyond the original tumour. Such a biopsy can detect lingering disease and could serve as a guide for […]

6

Gene variants increase risk of Addison’s disease

Variants of nine genes increase the risk of developing Addison’s disease, a rare disease in which the immune system attacks the adrenal glands. That is according to the largest genetic study to date on patients with Addison’s disease. The findings help increase knowledge about what causes the disease. The study was conducted by researchers at […]

7

Algorithm that performs as accurately as dermatologists

A study has now been presented that boosts the evidence for using AI solutions in skin cancer diagnostics. With an algorithm they devised themselves, scientists at the University of Gothenburg show the capacity of technology to perform at the same level as dermatologists in assessing the severity of skin melanoma.

8

Detecting single molecules and diagnosing diseases with a smartphone

Biomarkers play a central role in the diagnosis of disease and assessment of its course. Among the markers now in use are genes, proteins, hormones, lipids and other classes of molecules. Biomarkers can be found in the blood, in cerebrospinal fluid, urine and various types of tissues, but most of them have one thing in […]

9

Study reveals mutations that drive therapy-related myeloid neoplasms in children

Children treated for cancer with approaches such as chemotherapy can develop therapyrelated myeloid neoplasms (a second type of cancer) with a dismal prognosis. Scientists at St. Jude Children’s Research Hospital have characterized the genomic abnormalities of 84 such myeloid neoplasms, with potential implications for early interventions to stop the disease. A paper detailing the work […]