The scientists found that AKIRIN2 was consistently associated with the proteasome and not only required for the regulation of MYC, but of many more short-lived proteins. To their surprise, they found that AKIRIN2 only affected nuclear proteins, which accumulated freely in its absence. Thus, they hypothesised that AKIRIN2 might help the proteasome to enter the […]
Scientists at the Research Institute of Molecular Pathology (IMP) in Vienna have developed a CRISPR-Cas9 screening assay that allows to systematically pinpoint regulators of any gene of interest, including cancer-related genes. Using this approach, they discovered how cells transport their clean-up machinery, the proteasome, into the nucleus to maintain protein balance and get rid of […]
CN Bio, a leading organ-on-a-chip company that designs and manufactures single- and multi-organ microphysiological systems (MPS), has launched its Oncology Service in response to the global need to improve cancer drug discovery approval rates.
Evonetix, the synthetic biology company developing a desktop platform for scalable, high-fidelity and rapid gene synthesis, has been granted patent GB 2576304 for its novel method for DNA data storage and retrieval.
FUJIFILM Irvine Scientific, has completed construction and started the commissioning phase of its new manufacturing facility in Tilburg, the Netherlands. The commissioning milestone marks the beginning of validating the facility and equipment in anticipation of full operations starting in late 2021. The new facility will join manufacturing locations in the U.S. and Japan to increase […]
Selux Diagnostics, which is leading a new era in personalized diagnostics to combat superbug infections and fight antibiotic resistance, has received a $2.8 million award from the U.S. National Institutes of Health (NIH) to help the company commercialize its NextGen ‘Phenotyping’ (NGP) platform for rapid antimicrobial susceptibility testing (AST). Having recently completed its first clinical […]
SPT Labtech, a global leader in the design and development of automated instrumentation and consumables for life science applications, has unveiled new branding that brings together its technologies with those from recent acquisitions into a single entity. The merged portfolio and positioning reflect SPT Labtech’s commitment to harnessing the ingenuity and product development track record […]
The Sysmex Group, international manufacturer and provider of innovative analytical instruments and services for laboratory diagnostics, is on a continuous course of growth and innovation. To accommodate this development, Sysmex Europe will relocate its headquarters for the EMEA region (Europe, Middle East and Africa) from Norderstedt to Hamburg.
Waters Corporation and Sartorius will partner to provide bioprocess experts with direct access to high-quality mass spectrometry (MS) data to accelerate the speed and improve the accuracy of biopharmaceutical process development. Sartorius and Waters will partner to implement the BioAccord LC-MS System from Waters as a new bioprocess analyser with data connectivity to Sartorius’ Ambr […]
BioPharma Dynamics, a leading life sciences solution provider, has opened a new ISO Class 7 cleanroom facility located at new headquarters in Salford, Greater Manchester. This expansion sees the company treble in size, with its new premises adding the capacity for product assembly and increased warehouse and office space.