Approaches, significance and challenges Cell proliferation is a hallmark of cancer associated with aggressiveness and response to chemotherapy. In breast cancer (BC), assessment of proliferation constitutes the main component of grading and help in management. Herein, we address the most common approaches for BC proliferation assessment, their limitations, and evolving applications to overcome these challenges.
The in situ stage of conjunctival squamous cell carcinoma is called conjunctival squamous intraepithelial neoplasia (CSIN). The use of terms such as Bowen’s disease and ocular surface squamous neoplasia are discouraged as their meanings vary and are prone to misinterpretation. The severity of squamous epithelial dysplasia is graded by the proportion of involved surface epithelium. […]
The recent COVID-19 pandemic and race to develop vaccines against the causative agent, severe acute respiratory syndrome coronavirus 2, has reminded us of the important role that protein glycosylation plays in the mechanisms of pathogen infection and host immune response. CLI caught up with Dr Sanda and Dr Campos (both at Team Scientific Service Group […]
The impact of the microbiome on a person’s health and disease is only slowly being fully realized. Here Bio-Me introduce themselves and their work to factor in the microbiome to the delivery of precision medicine.
Secretoneurin is a small neuropeptide detectable in the blood and is strong predictor for mortality in several patient cohorts with underlying cardiovascular disease. Here, CardiNor introduce themselves and their work to develop a secretoneurin test to use as part of a biomarker panel for cardiovascular disease.
Scientific and technical advances in the field of Microchip Imaging Cytometry (MIC) are set to advance quantitative diagnostic testing that may deliver more economical, easy-to-use, and accessible healthcare to the public, according to a new article published in Opto-Electronic Advances .
As the cannabis derivative delta-8-THC grows in popularity, it’s important for drug tests to be able to detect and differentiate it from delta-9-THC – the primary psychoactive ingredient in cannabis. Breaking research showcased at the 2022 AACC Annual Scientific Meeting & Clinical Lab Expo demonstrates that common drug testing methods can do just that.
A first-of-its-kind test could make it easier for newborns to get care for spinal muscular atrophy, a common genetic disease that is life-threatening but treatable if caught in time. Findings on this method and a second innovative test that could improve diagnosis of paediatric urinary tract infections (UTIs) were discussed at the 2022 AACC Annual […]
New research shows that removing a race modifier from a formula used to diagnose kidney disease could lead to more equitable care for Black patients. This study and a second that examines how this same diagnostic approach impacts Asian patients was presented at the 2022 AACC Annual Scientific Meeting & Clinical Lab Expo.
AACC welcomed thousands of medical professionals and healthcare leaders to the 2022 AACC Annual Scientific Meeting & Clinical Lab Expo at the McCormick Place Convention Center in Chicago from July 24-28. The meeting featured ground-breaking diagnostic advances that will help solve challenging patient health problems, and affirmed just how essential laboratory medicine professionals are to […]