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Novel nephrological markers: anti-PLA2R, anti-THSD7A and uromodulin

Autoantibody diagnostics have in recent years transformed the diagnosis of the rare kidney disease primary membranous nephropathy (MN). The identification of the target antigens M-type phospholipase A2 receptor (PLA2R) and thrombospondin type 1-domain-containing 7A (THSD7A) paved the way for the development of specific immunological assays to detect the corresponding antibodies. Determination of both anti-PLA2R and […]