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Pharmacogenetic testing of CYP2C19 associated with clopidogrel therapy

Because of the critical nature of the reported clinical events (such as stent thrombosis and hemorrhage) associated with patients with certain cytochrome p450 2C19 (CYP2C19) variants receiving clopidogrel therapy, additional clinical studies are warranted. Large scale clinical trials seeking to correlate patient’s response to clopidogrel (Plavix®) with the CYP2C19 genotype may benefit from the inclusion […]