{"id":1066,"date":"2020-08-26T09:33:00","date_gmt":"2020-08-26T09:33:00","guid":{"rendered":"https:\/\/clinlabint.3wstaging.nl\/new-eye-test-detects-earliest-signs-of-glaucoma\/"},"modified":"2021-01-08T11:09:29","modified_gmt":"2021-01-08T11:09:29","slug":"new-eye-test-detects-earliest-signs-of-glaucoma","status":"publish","type":"post","link":"https:\/\/clinlabint.com\/new-eye-test-detects-earliest-signs-of-glaucoma\/","title":{"rendered":"New eye test detects earliest signs of glaucoma"},"content":{"rendered":"<p><span lang=\"EN-GB\">The Wellcome-funded diagnostic \u2013 developed by researchers at University College London (UCL) and the Western Eye Hospital \u2013 allows doctors to see individual nerve cell death in the back of the eye.<\/span><br \/>\n<span lang=\"EN-GB\">Early detection means doctors can start treatment before sight loss begins. The test also has potential for early diagnosis of other degenerative neurological conditions, including Parkinson\u2019s, Alzheimer\u2019s and multiple sclerosis.<\/span><br \/>\n<span lang=\"EN-GB\">Professor Francesca Cordeiro, at UCL Institute of Opthamology, who led the research, said: &quot;Although detection has been improving, most patients have lost a third of vision by the time they are diagnosed.<\/span><br \/>\n<span lang=\"EN-GB\">&quot;Now, for the first time, we have been able to show individual cell death and detect the earliest signs of glaucoma. While we cannot cure the disease, our test means treatment can start before symptoms begin.&quot;<\/span><br \/>\n<span lang=\"EN-GB\">Glaucoma affects 60 million people worldwide and one in ten go blind.<\/span><br \/>\n<span lang=\"EN-GB\">The new technique means patients could be diagnosed up to ten years earlier than is currently possible.<\/span><br \/>\n<span lang=\"EN-GB\">Bethan Hughes, Wellcome\u2019s Strategic Development Lead for Innovation, said: &quot;This innovation has the potential to transform lives for those who suffer loss of sight through glaucoma, and offers hope of a breakthrough in early diagnosis of other neurodegenerative diseases.&quot;<\/span><br \/>\n<span lang=\"EN-GB\">Loss of sight in patients with glaucoma is caused by the death of cells in the retina at the back of the eye \u2013 apoptosis.<\/span><br \/>\n<span lang=\"EN-GB\">The new technique is called DARC, which stands for detection of apoptosing retinal cells.<\/span><br \/>\n<span lang=\"EN-GB\">It uses a specially developed fluorescent marker which attaches to cell proteins when it\u2019s injected into patients. Damaged retinal cells appear as white fluorescent spots during eye examination.<\/span><br \/>\n<span lang=\"EN-GB\">Initial clinical trials were carried out on a small number of glaucoma patients and compared with tests on healthy people to establish the test\u2019s safety.<\/span><br \/>\n<span lang=\"EN-GB\">DARC uses equipment that is already part of routine hospital eye examinations.<\/span><br \/>\n<span lang=\"EN-GB\">The researchers hope that eventually it may be possible for opticians to do the tests. This would mean even earlier detection of the disease.<\/span><br \/>\n<span lang=\"EN-GB\">Treatment for glaucoma is much more successful when it is begun in the early stages of the disease.<\/span><br \/>\n<span lang=\"EN-GB\">Further studies will now be carried out into DARC and how it could be used to detect other neurodegenerative conditions where increasing numbers of nerve cells are lost as the disease progresses.<\/span><\/p>\n<p><span lang=\"EN-GB\">Wellcome Trust<\/span><br \/>\n<span lang=\"EN-GB\"><link https:\/\/wellcome.ac.uk\/news\/new-eye-test-detects-earliest-signs-glaucoma _blank external-link-new-window \"Opens external link in new window\">wellcome.ac.uk\/news\/new-eye-test-detects-earliest-signs-glaucoma<\/link><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Wellcome-funded diagnostic \u2013 developed by researchers at University College London (UCL) and the Western Eye Hospital \u2013 allows doctors to see individual nerve cell death in the back of the eye. Early detection means doctors can start treatment before sight loss begins. The test also has potential for early diagnosis of other degenerative neurological [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[35],"tags":[],"_links":{"self":[{"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/posts\/1066"}],"collection":[{"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/comments?post=1066"}],"version-history":[{"count":0,"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/posts\/1066\/revisions"}],"wp:attachment":[{"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/media?parent=1066"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/categories?post=1066"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/tags?post=1066"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}