{"id":1607,"date":"2020-08-26T09:34:41","date_gmt":"2020-08-26T09:34:41","guid":{"rendered":"https:\/\/clinlabint.3wstaging.nl\/researchers-reveal-treasure-trove-of-genes-key-to-kidney-cancer\/"},"modified":"2021-01-08T11:11:50","modified_gmt":"2021-01-08T11:11:50","slug":"researchers-reveal-treasure-trove-of-genes-key-to-kidney-cancer","status":"publish","type":"post","link":"https:\/\/clinlabint.com\/researchers-reveal-treasure-trove-of-genes-key-to-kidney-cancer\/","title":{"rendered":"Researchers reveal treasure trove of genes key to kidney cancer"},"content":{"rendered":"<p>A genomic analysis of clear cell renal cell carcinoma (ccRCC), the most common form of kidney cancer, from 72 patients has uncovered 31 genes that are key to development, growth and spread of the cancer, say researchers from Mayo Clinic in Florida. Eight of these genes had not been previously linked to kidney cancer, and six other genes were never known to be involved in any form of cancer.<\/p>\n<p>Their stud is the most extensive analysis to date of gene expression\u2019s role in ccRCC tumor growth and metastasis. The ccRCC subtype accounts for 80 percent of all kidney cancer cases.<br \/>\nThis study is a thorough analysis, because overexpressed genes were functionally tested in kidney cancer cells to ensure they were important to some aspect of the cancer process, says the study\u2019s senior investigator, molecular biologist, John A. Copland, Ph.D.<\/p>\n<p>\u201cThe power of this study is that we looked at genes discovered to be over-expressed in patients\u2019 tumours and determined their function in kidney cancer, which has not been done on a large scale before,\u201d he says. \u201cThis is a seminal step in identifying key pathways and molecules involved in kidney cancer so that specific therapies that target these new genes can be developed to treat this cancer.\u201d\n<link http:\/\/newsnetwork.mayoclinic.org\/discussion\/mayo-clinic-researchers-reveal-treasure-trove-of-genes-key-to-kidney-cancer - external-link-new-window>Mayo Clinic<\/link>\n","protected":false},"excerpt":{"rendered":"<p>A genomic analysis of clear cell renal cell carcinoma (ccRCC), the most common form of kidney cancer, from 72 patients has uncovered 31 genes that are key to development, growth and spread of the cancer, say researchers from Mayo Clinic in Florida. Eight of these genes had not been previously linked to kidney cancer, and [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[35],"tags":[],"_links":{"self":[{"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/posts\/1607"}],"collection":[{"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/comments?post=1607"}],"version-history":[{"count":0,"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/posts\/1607\/revisions"}],"wp:attachment":[{"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/media?parent=1607"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/categories?post=1607"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/tags?post=1607"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}