{"id":16384,"date":"2022-01-18T13:20:53","date_gmt":"2022-01-18T13:20:53","guid":{"rendered":"https:\/\/clinlabint.com\/?p=16384"},"modified":"2022-01-20T12:36:55","modified_gmt":"2022-01-20T12:36:55","slug":"people-with-ibd-have-more-microplastics-in-their-faeces-study-finds","status":"publish","type":"post","link":"https:\/\/clinlabint.com\/people-with-ibd-have-more-microplastics-in-their-faeces-study-finds\/","title":{"rendered":"People with IBD have more microplastics in their faeces, study finds"},"content":{"rendered":"
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People with IBD have more microplastics in their faeces, study finds<\/h1>\/ in E-News<\/a> <\/span><\/span><\/header>\n<\/div><\/section>
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Microplastics \u2013 tiny pieces of plastic less than 5 mm in length \u2013 are everywhere, from bottled water to food to air. They have been found in the deepest part of the ocean and the top of Mount Everest. According to recent estimates, people consume tens of thousands of these particles each year, with unknown health consequences. Now, researchers reporting in Environmental Science & Technology found that people with inflammatory bowel disease (IBD) have more microplastics in their faeces than healthy controls, suggesting that the fragments could be related to the disease process.<\/p>\n

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The prevalence of IBD, which includes Crohn\u2019s disease and ulcerative colitis, is rising globally. Characterized by chronic inflammation of the digestive tract, IBD can be triggered or made worse by diet and environmental factors. It has been shown that microplastics can cause intestinal inflammation, gut microbiome disturbances and other problems in animal models, so Faming Zhang, Yan Zhang and colleagues wondered if they could also contribute to IBD. As a first step toward finding out, the researchers wanted to compare the levels of microplastics in faeces from healthy subjects and people with different severities of IBD.<\/p>\n

The team obtained faecal samples from 50 healthy people and 52 people with IBD from different geographic regions of China. Analysis of the samples showed that faeces from IBD patients contained about 1.5 times more microplastic particles per gram than those from healthy subjects. The microplastics had similar shapes (mostly sheets and fibres) in the two groups, but the IBD faeces had more small (less than 50 \u03bcm) particles. The two most common types of plastic in both groups were polyethylene terephthalate (PET; used in bottles and food containers) and polyamide (PA; found in food packaging and textiles).<\/p>\n

People with more severe IBD symptoms tended to have higher levels of faecal microplastics. Through a questionnaire, the researchers found that people in both groups who drank bottled water, ate takeaway food and were often exposed to dust had more microplastics in their faeces. These results suggest that people with IBD may be exposed to more microplastics in their gastrointestinal tract. However, it\u2019s still unclear whether this exposure could cause or contribute to IBD, or whether people with IBD accumulate more faecal microplastics as a result of their disease, the researchers say.<\/p>\n<\/div><\/section>
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Higher numbers of microplastics of various shapes, such as sheets (left) and fibres (right) were found in the faeces of people with IBD than in healthy controls. Credit: Adapted from Environmental Science & Technology 2021, doi: 10.1021\/acs.est.1c03924<\/p>\n<\/div><\/div><\/div>\"\"<\/div><\/div><\/div>
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