A race to unlock genetic clues behind living to 100 is set to begin next year, after a US team announced it will compete for the $10m Genomics X Prize. Genetic entrepreneur Dr Jonathan Rothberg is entering the challenge to identify genes linked to a long, healthy life. His team – and any other contenders – will be given 30 days to work out the full DNA code of 100 centenarians at a cost of no more than $1,000 per genome.
\nThe race will start in September 2013. Under the rules of the Archon Genomics X Prize, teams have until next May to register for the competition. Dr Rothberg’s team from Life Technologies Corporation in California is the first to formally enter the race.
\nHis latest business venture, Ion Torrent, makes the Personal Genome Machine and the Ion Proton sequencer
\nRothberg claims his machines can sequence DNA more quickly and cheaply than ever thought possible
\nThe Ion Proton sequencer will be used for the challenge. Being able to sequence the full human genome at a cost of $1,000 or less is regarded as a milestone in science.
\nIt is seen as the threshold at which DNA sequencing technology becomes cheap enough to be used widely in medicine, helping in diagnosis and in matching drugs to a patient’s genetic make-up.
\n‘
\nOne hundred people aged 100 have donated their DNA for the project.
\nScientists believe people who reach a very old age may have certain rare changes in their genes which protect against common diseases of later life, such as heart disease and cancer. If these genes can be identified by analysing the DNA codes of centenarians, it will help scientists search for new medical treatments and perhaps ways to prolong life. However, many sample DNA sequences will be needed in order to get the accuracy needed to pinpoint changes on the scale of a few genetic letters among the three billion in the human genome.
\nDr Jonathan Rothberg, a geneticist and entrepreneur, said the DNA of 100 centenarians is a good start towards finding ‘the fountains of youth’.
\nHe told BBC News: ‘One hundred people will give you a hint. One thousand will make you reasonably sure. Ten thousand will let you say, ‘Hey, these are the genes involved in cancer or heart disease”.
\nDr Craig Venter is the originator of the prize and one of the main players in the race to sequence the first human genome, which was completed in 2003.\nBBC<\/link>\n","protected":false},"excerpt":{"rendered":"
A race to unlock genetic clues behind living to 100 is set to begin next year, after a US team announced it will compete for the $10m Genomics X Prize. Genetic entrepreneur Dr Jonathan Rothberg is entering the challenge to identify genes linked to a long, healthy life. His team – and any other contenders […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[35],"tags":[],"_links":{"self":[{"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/posts\/2049"}],"collection":[{"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/comments?post=2049"}],"version-history":[{"count":0,"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/posts\/2049\/revisions"}],"wp:attachment":[{"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/media?parent=2049"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/categories?post=2049"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/tags?post=2049"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}