{"id":20731,"date":"2023-11-08T16:11:01","date_gmt":"2023-11-08T16:11:01","guid":{"rendered":"https:\/\/clinlabint.com\/?p=20731"},"modified":"2023-11-08T16:12:24","modified_gmt":"2023-11-08T16:12:24","slug":"amsbio-introduces-disposable-bioreactor-for-induced-pluripotent-stem-cell-spheroid-culture","status":"publish","type":"post","link":"https:\/\/clinlabint.com\/amsbio-introduces-disposable-bioreactor-for-induced-pluripotent-stem-cell-spheroid-culture\/","title":{"rendered":"AMSBIO introduces disposable bioreactor for induced pluripotent stem cell spheroid culture"},"content":{"rendered":"
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AMSBIO introduces disposable bioreactor for induced pluripotent stem cell spheroid culture<\/h1>\/ in Product News<\/a> <\/span><\/span><\/header>\n<\/div><\/section>
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The new ABLE 3D Magnetic Stir and Disposable Bioreactor System from AMSBIO provides cost-effective, lab-scale production of induced pluripotent stem cell (iPSC) spheroid culture.<\/strong><\/p>\n

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Induced pluripotent stem cells grown in 3D spheroid suspension culture closely resemble embryoid body structures naturally formed by embryonic stem cells. Using an ABLE 3D Bioreactor offers researchers an easy-to-use and affordable tool that provides excellent yield, viability, and high efficiency for the expansion of human iPSCs and differentiation.<\/p>\n

Made of high-density polycarbonate for bio-compatibility with iPSC cultivation, the Bio-reactor comes ready-to-use for non-adherent cell growth, eliminating the need for high-priced extracellular matrix proteins for coating plasticware. A delta-wing-shaped impeller with a magnet on each blade, located within the bio-reactor, provides low shear agitation by laminar flow, encouraging the formation and growth of uniform 200-300 \u03bcm spheroid cell clusters.<\/p>\n

The bioreactor system uses disposable vessels for cell culturing or production of up to 5 \u00d7 107 cells per 30 mL vessel, equivalent to cell yield from ten 10 cm culture dishes or ten 6-well plates.<\/p>\n

The ABLE 3D bioreactor seamlessly integrates with StemFit media, a chemically defined stem cell culture media proven to effectively maintain iPSCs and embryonic stem cells under feeder-free conditions. Human iPSCs, when maintained on iMatrix-511-coated plates along with StemFit media, can be effortlessly harvested and dissociated into single cells. These single cells are then ready for a smooth transition into the ABLE 3D Bioreactor system for large scale and efficient iPSC spheroid culture.<\/p>\n

For more information, visit: https:\/\/www.amsbio.com\/able-bioreactor<\/a><\/p>\n

Digital issue: Please click here<\/a> for more information<\/p>\n<\/div><\/section>
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