{"id":21301,"date":"2024-03-18T09:46:49","date_gmt":"2024-03-18T09:46:49","guid":{"rendered":"https:\/\/clinlabint.com\/?p=21301"},"modified":"2024-03-18T09:46:49","modified_gmt":"2024-03-18T09:46:49","slug":"lab-spun-sponges-form-perfect-scaffolds-for-growing-skin-cells-to-heal-wounds","status":"publish","type":"post","link":"https:\/\/clinlabint.com\/lab-spun-sponges-form-perfect-scaffolds-for-growing-skin-cells-to-heal-wounds\/","title":{"rendered":"Lab-spun sponges form perfect scaffolds for growing skin cells to heal wounds"},"content":{"rendered":"
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\r\n\"Bio-Rad<\/a>\r\n<\/p>\n<\/div><\/section><\/div>

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Lab-spun sponges form perfect scaffolds for growing skin cells to heal wounds<\/h1>\/ in E-News<\/a> <\/span><\/span><\/header>\n<\/div><\/section>
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A new technique for electrospinning sponges has allowed scientists from the University of Surrey to directly produce 3D scaffolds \u2013 on which skin grafts could be grown from the patient\u2019s own skin.<\/h3>\n

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Chloe Howard, from Surrey\u2019s School of Computer Science and Electronic Engineering said: \u201cAfter spinning these scaffolds, we grew skin cells on them. Seven days later, they were twice as viable as cells grown on 2D films or mats. They even did better than cells grown on plasma-treated polystyrene \u2013 previously, the gold standard. They were very happy cells on our 3D scaffolds!<\/p>\n

\u201cOur findings pave the way for harvesting a patient\u2019s own skin cells and multiplying them. These grafts could treat chronic wounds better and faster.\u201d<\/p>\n

Scientists prepared a solution which included gelatin and polyaprolactone (PCL) – a biodegradable polymer which is known to be compatible with human tissue. They pumped this solution through a syringe into an electrical field, which stretched it into nanofibres.<\/p>\n

This process is simple, scalable, and cheap. The researchers now hope it can be used in other medical applications.<\/p>\n

Dr Vlad Stolojan, Associate Professor in Surrey\u2019s Advanced Technology Institute, said: \u201cElectrospinning is extremely adaptable. We can mimic the way that muscle fibres behave by spinning fibres that align in the same direction. This technique could one day create artificial skin, bone and cartilage too \u2013 helping people recover from wounds quicker, and with better long-term results.\u201d<\/p>\n

The research is published in the journal Nanomaterials [1].<\/p>\n

Reference:<\/strong><\/em>
\n1. Howard, C.J.; Paul, A.; Duruanyanwu, J.; et. al. The Manufacturing Conditions for the Direct and Reproducible Formation of Electrospun PCL\/Gelatine 3D Structures for Tissue Regeneration. Nanomaterials 2023, 13, 3107.\u00a0 doi: https:\/\/doi.org\/10.3390\/nano13243107<\/a><\/em><\/p>\n<\/div><\/section>
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