{"id":22307,"date":"2024-10-23T14:50:30","date_gmt":"2024-10-23T14:50:30","guid":{"rendered":"https:\/\/clinlabint.com\/?p=22307"},"modified":"2024-10-23T14:50:30","modified_gmt":"2024-10-23T14:50:30","slug":"vapourtec-launches-specialised-uv-detector-for-peptide-synthesis-and-flow-chemistry","status":"publish","type":"post","link":"https:\/\/clinlabint.com\/vapourtec-launches-specialised-uv-detector-for-peptide-synthesis-and-flow-chemistry\/","title":{"rendered":"Vapourtec launches specialised UV detector for peptide synthesis and flow chemistry"},"content":{"rendered":"
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Vapourtec launches specialised UV detector for peptide synthesis and flow chemistry<\/h1>\/ in Product News<\/a> <\/span><\/span><\/header>\n<\/div><\/section>
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New device aims to enhance efficiency in pharmaceutical research and development<\/strong><\/p>\n

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Vapourtec, a company known for its innovations in flow chemistry equipment, has developed a new online UV detector specifically designed for peptide synthesis and flow chemistry applications. The device, named Fmoc-UV, addresses the unique challenges faced by researchers in these fields.<\/p>\n

Robust design for demanding environments<\/h4>\n

Unlike traditional UV detectors optimised for high-performance liquid chromatography (HPLC), the Fmoc-UV is built to withstand the harsh conditions often encountered in flow chemistry. Dr Manuel Nu\u00f1o, Chief Scientific Officer at Vapourtec, explains the rationale behind the design: \u201cFlow chemistry applications, by contrast, require the use of corrosive reagents, often at high concentrations.\u201d<\/p>\n

The detector features a durable construction with no moving parts, enhancing its reliability in challenging laboratory settings. Additionally, it incorporates a low-cost, easily replaceable flow cell to mitigate issues arising from potential blockages.<\/p>\n

Tailored wavelengths for specific applications<\/h4>\n

The Fmoc-UV operates at two distinct wavelengths: 365 nm and 460 nm. The former is intended for quantifying the fluorenylmethoxycarbonyl (Fmoc) protecting group commonly used in solid-phase peptide synthesis (SPPS). The latter wavelength is optimised for detecting the 4-Methyltrityl (Mtt) group, which plays a crucial role in the synthesis of certain active pharmaceutical ingredients (APIs), including semaglutide.<\/p>\n

With a high acquisition rate of 4 Hz, the detector offers precise monitoring of these protecting groups during the synthesis process.<\/p>\n

Versatility in research settings<\/h4>\n

While primarily designed for peptide synthesis, the Fmoc-UV demonstrates versatility across various chemical applications. Dr Nu\u00f1o notes: \u201cDesigned for peptide synthesis, the Fmoc-UV is also suitable for other applications in both flow and batch chemistry environments where we can easily perform online sampling of batch reactors.\u201d<\/p>\n

The device\u2019s compatibility with Vapourtec\u2019s R-Series software and its ability to communicate via RS232 protocols further enhance its integration into existing laboratory setups.<\/p>\n

For more information, visit: www.vapourtec.com<\/a><\/p>\n

Digital issue: Please click here<\/a> for more information<\/p>\n<\/div><\/section>
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