{"id":4129,"date":"2020-08-26T09:18:52","date_gmt":"2020-08-26T09:18:52","guid":{"rendered":"https:\/\/clinlabint.3wstaging.nl\/randox-cystatin-c-providing-a-true-reflection-of-renal-function\/"},"modified":"2021-01-08T11:27:54","modified_gmt":"2021-01-08T11:27:54","slug":"randox-cystatin-c-providing-a-true-reflection-of-renal-function","status":"publish","type":"post","link":"https:\/\/clinlabint.com\/randox-cystatin-c-providing-a-true-reflection-of-renal-function\/","title":{"rendered":"Randox Cystatin C-Providing a true reflection of renal function"},"content":{"rendered":"
Did you know that up to 50% of renal function can be lost before significant creatinine elevation occurs? Unlike creatinine, Cystatin C does not suffer from this \u2018blind area\u2019. Cystatin C is extremely sensitive to very small changes in GFR and is therefore capable of detecting early stage kidney dysfunction. Furthermore, Cystatin C is a particularly useful marker of renal function in patients where creatinine measurements are not suitable e.g. individuals who are obese, malnourished, have liver cirrhosis or reduced muscle mass.<\/p>\n
Cystatin C is a small (13 kDa) cysteine proteinase inhibitor that is produced at a constant rate by all nucleated cells. The small molecular weight of Cystatin C allows it to be completely removed and broken down by the kidneys, levels therefore remain steady if the kidneys are working efficiently and the Glomerular Filtration Rate (GFR) is normal. <\/p>\n
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\nSupplier:<\/strong> Randox Laboratories Ltd.
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