{"id":4366,"date":"2020-08-26T09:19:53","date_gmt":"2020-08-26T09:19:53","guid":{"rendered":"https:\/\/clinlabint.3wstaging.nl\/c-difficile-gdh-detection\/"},"modified":"2021-01-08T11:29:03","modified_gmt":"2021-01-08T11:29:03","slug":"c-difficile-gdh-detection","status":"publish","type":"post","link":"https:\/\/clinlabint.com\/c-difficile-gdh-detection\/","title":{"rendered":"C. difficile GDH detection"},"content":{"rendered":"<p><em>Clostridium difficile<\/em> is an anaerobic bacteria that grows in the intestine when the normal flora has been altered by treatment with antibiotics. Only toxigenic strains cause infections from mild-diarrhea to pseudomembranous colitis, potentially leading to death. Detection of Glutamate Dehydrogenase (GDH) that is an antigen marker of <em>C.difficile<\/em> proliferation allows significant cost reduction in lab diagnosis for suspected <em>C.difficile<\/em> samples. Positive GDH samples should be investigated further to test for the toxins A or\/and B. The Coris C. diff-Strip is a ready-to-use immunochromatographic test that allows the specific detection of <em>C.difficile<\/em> GDH in stool specimens in a strip format. When the fecal suspension comes into contact with the strip, the solubilized conjugate migrates with the sample and both reagents come into contact with the anti-<em>Clostridium <\/em>GDH antibody adsorbed onto the nitrocellulose. If the sample contains <em>C.difficile<\/em> GDH, a red line develops. The result is visible within 15 minutes.<br \/>\n<!--more--><br \/>\n<strong>Supplier:<\/strong> Coris Bioconcept<br \/>\n<strong>Website:<\/strong> <a href=\"\" target=\"_blank\" rel=\"noopener noreferrer\"><\/a><\/p>\n<p><a class=\"avia-button avia-color-theme-color\" href=\"mailto:thomas.leclipteux@corisbio.com\">Mail the supplier<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Clostridium difficile is an anaerobic bacteria that grows in the intestine when the normal flora has been altered by treatment with antibiotics. Only toxigenic strains cause infections from mild-diarrhea to pseudomembranous colitis, potentially leading to death. Detection of Glutamate Dehydrogenase (GDH) that is an antigen marker of C.difficile proliferation allows significant cost reduction in lab [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":10317,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[39],"tags":[],"_links":{"self":[{"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/posts\/4366"}],"collection":[{"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/comments?post=4366"}],"version-history":[{"count":0,"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/posts\/4366\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/media\/10317"}],"wp:attachment":[{"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/media?parent=4366"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/categories?post=4366"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/tags?post=4366"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}