{"id":4512,"date":"2020-08-26T09:20:54","date_gmt":"2020-08-26T09:20:54","guid":{"rendered":"https:\/\/clinlabint.3wstaging.nl\/enzymatic-creatinine-assay-for-automated-clinical-chemistry-analysers\/"},"modified":"2021-01-08T11:29:44","modified_gmt":"2021-01-08T11:29:44","slug":"enzymatic-creatinine-assay-for-automated-clinical-chemistry-analysers","status":"publish","type":"post","link":"https:\/\/clinlabint.com\/enzymatic-creatinine-assay-for-automated-clinical-chemistry-analysers\/","title":{"rendered":"Enzymatic creatinine assay for automated clinical chemistry analysers"},"content":{"rendered":"
The measurement of creatinine is commonly used to assess renal function and estimate glomerular filtration rates (eGFR). Jaffe methods, however, tend to be imprecise and are prone to a variety of interferences which may lead to inaccurate eGFR calculations. A new enzymatic creatinine assay, which minimises these problems and offers superior performance to the older Jaffe methods, is available for use on automated clinical chemistry analysers. This 2-part, liquid stable reagent eliminates interferences from endogenous creatine and ascorbic acid. In addition haemoglobin to 500mg\/dL, conjugated bilirubin to 32mg\/dL and unconjugated bilirubin to 40mg\/dL do not to interfere with the assay. The reagent has an 18 month shelf life and up to 30 day on-board stability. The assay is measured at 550nm, correlates well to Jaffe methods (r=0.999) and is linear to 30mg\/dL. Studies conducted according to NCCLS: EP 5 protocol yielded excellent precision with CVs below 2%. Many instrument
applications are available.
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\nSupplier:<\/strong> Medtest\/Pointe Scientific
\nWebsite:<\/strong> <\/a><\/p>\n