{"id":957,"date":"2020-08-26T09:32:39","date_gmt":"2020-08-26T09:32:39","guid":{"rendered":"https:\/\/clinlabint.3wstaging.nl\/genetic-testing-recommended-for-children-considered-at-risk-for-most-common-eye-cancer\/"},"modified":"2021-01-08T11:09:04","modified_gmt":"2021-01-08T11:09:04","slug":"genetic-testing-recommended-for-children-considered-at-risk-for-most-common-eye-cancer","status":"publish","type":"post","link":"https:\/\/clinlabint.com\/genetic-testing-recommended-for-children-considered-at-risk-for-most-common-eye-cancer\/","title":{"rendered":"Genetic testing recommended for children considered at risk for most common eye cancer"},"content":{"rendered":"

Children who are considered to be at risk of developing eye cancer should receive genetic counselling and testing as soon as possible to clarify risk for the disease. This is the consensus of leading ophthalmologists, pathologists and geneticists, who worked for two years to develop the first U.S. guidelines on how to screen for the most common eye tumour affecting children. The goal is to ensure retinoblastoma is detected at the earliest possible stage so ophthalmologists can save the lives and vision of more children. <\/span>
\nRetinoblastoma is a cancer that starts in the retina, the very back of the eye. It can also spread to other parts of the body, including the brain and bones. There are approximately 350 new cases diagnosed each year in the United States. <\/span>
\nThe disease primarily affects young children. It can be either hereditary or non-hereditary. Children with hereditary retinoblastoma often develop retinal tumours in both eyes within the first years of life. Early diagnosis, when tumours are small, improves the child\u2019s chance of survival and their chance of keeping their vision and their eyes. <\/span>
\nDevelopment of these guidelines began when ophthalmologist Alison Skalet, M.D., Ph.D., of the Casey Eye Institute in Portland, Ore., searched for an optimal screening strategy for her own patients and found little published guidance. <\/span>
\nFor the next two years, Dr. Skalet and Patricia Ch\u00e9vez-Barrios, M.D., ophthalmologist, and pathologist from Houston Methodist Hospital, led members of the American Association of Ophthalmic Oncologists and Pathologists, and a team of experts to devise guidelines. The effort was also supported by the American Association for Pediatric Ophthalmology and Strabismus, the American Academy of Ophthalmology, and the American Academy of Pediatrics. <\/span>
\nThe guidelines address a knowledge gap among ophthalmologists and other health care professionals in the U.S. regarding risk for inherited retinoblastoma and best practices for screening examinations. It is anticipated that they will also influence care in other countries. Therefore, the guidelines were written to provide a general framework for care that can be modified based on local resources, and provider and parental preferences. The recommendations acknowledge paediatric anaesthesia and genetic testing may be limited in many developing countries, preventing strict adherence. So, the guidelines offer direction in cases when these resources are unavailable. <\/span>
\nDr. Ch\u00e9vez-Barrios said the new guidelines meet the team\u2019s goal to focus care on children at the highest risk for disease while decreasing unnecessary examinations for children at lower or no risk of developing retinoblastoma. <\/span>
\n\u201cWe wanted to make sure all the doctors who come in contact with these patients are aware of how to diagnose and treat them so we can save more eyes, more vision and of course more lives,\u201d said Dr. Ch\u00e9vez-Barrios. <\/span>
\nOphthalmologists say there are signs to look for that may indicate retinoblastoma. They include a white colour in the pupil when a light is shone in the eye, such as when taking a flash photograph. Also, eyes that appear to be looking in different directions could be a sign of trouble. They encourage parents to make an appointment with their child’s paediatrician if they notice any changes to their child’s eyes. <\/span><\/p>\n

American Academy of Ophthalmology<\/span>
\nwww.aao.org\/newsroom\/news-releases\/detail\/genetic-testing-for-children-at-risk-of-eye-cancer<\/link><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Children who are considered to be at risk of developing eye cancer should receive genetic counselling and testing as soon as possible to clarify risk for the disease. This is the consensus of leading ophthalmologists, pathologists and geneticists, who worked for two years to develop the first U.S. guidelines on how to screen for the […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[35],"tags":[],"_links":{"self":[{"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/posts\/957"}],"collection":[{"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/comments?post=957"}],"version-history":[{"count":0,"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/posts\/957\/revisions"}],"wp:attachment":[{"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/media?parent=957"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/categories?post=957"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/clinlabint.com\/wp-json\/wp\/v2\/tags?post=957"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}