horiba QSP

HORIBA introduces network option for digital morphology training tool for multiple user access in multiple locations

HORIBA UK has introduced a new network licence option for its QSP 2.0 (Quality Slide Program) [1] affordable digital tool for skill evaluation and training in morphology at IBMS Congress 2022. This now enables up to 50 users across various locations, even in different countries, to directly access this valuable digital morphology resource as it […]

cytena

CYTENA and ExcellGene to develop automated work-flows for biotherapeutics cell line development

CYTENA, a BICO group company and a leading provider of high-precision instruments for handling biological cells, will collaborate with ExcellGene, a leading biologics Contract Development & Manufacturing Organizations (CDMO) that manufactures recombinant proteins, to streamline cell line development workflows for highly-efficient monoclonal antibody (mAb) and complex therapeutic protein manufacturing, which enables important improvements to the […]

codexis seqwell

Codexis and seqWell announce partnership to accelerate commercialization of seqWell’s genomics workflow solutions

Codexis and seqWell have announced the initiation of a strategic partnership and investment to accelerate the commercialization of seqWell’s genomics workflow solutions. Codexis, a leading enzyme engineering company enabling the promise of synthetic biology, and seqWell, a developer of transformative library preparation products for demanding genomics applications, plan to collaborate on using Codexis’ CodeEvolver platform […]

biotium 5 22

Biotium acquires CAT5 FFPE RNA/DNA extraction technology from Cell Data Sciences

Biotium, a supplier of cutting-edge life science reagents, has acquired Cell Data Sciences RNAstorm and DNAstorm kits for RNA/DNA extraction. Biotium, which previously distributed the Cell Data Sciences kits, will now be their sole manufacturer. The extraction kits will be offered from the Biotium website and authorized distributors.

Arctoris

Arctoris and Evariste Technologies form a joint venture to identify novel small molecule cMET Inhibitors for Non-Small Cell Lung Cancer

Arctoris, a tech-enabled biopharma company, and Evariste Technologies, an AI-drug discovery company, have formed a joint venture to identify novel small molecule kinase inhibitors for treatment of patients with Non-Small Cell Lung Cancer (NSCLC). 

shutterstock 125266409

Insight into the importance of controls in molecular diagnostics assays

Controls are a crucial part of any assay. Without them, our work is, at best, simply a waste of time and reagents. We know we need them but we probably should give them much more thought than we do. CLI caught up with Dr John Hedges, Director of Research and Development at Asuragen (a Bio-Techne […]

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PCR allows rapid, differentiated dermatomycosis diagnostics

The diagnosis of fungal infections of the skin and nails has undergone a paradigm shift in recent years. Traditional culturing methods have in many cases been replaced by PCR-based diagnostics, which provide greater accuracy and yield results ina fraction of the time. The fast, differentiated detection of dermatomycosis pathogens enables prompt targeted treatment of infections.

Fig1.GenomicSubtypes

Molecular subtypes of metastatic urothelial carcinoma and treatment options

Urothelial carcinoma is a common cancer and patients with metastatic urothelial cancer (mUC) have very poor outcomes. Many mUC patients do not have durable responses to systemic treatment and are exposed to toxic side effects that negatively impact the patient’s quality of life. Identifying novel biomarkers for therapy and selecting the best treatment option for […]

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Two common peak-integration protocols for the quantification of M-proteins in serum protein electrophoresis

Quantification of M-proteins plays an important role in diagnosing and managing patients with monoclonal gammopathies. This is traditionally performed by integrating abnormal monoclonal peaks in the electrophoretogram, using either a perpendicular drop (PD) or tangential skim (TS) method. In this article, we describe the advantages and disadvantages of the PD and TS integration methods and […]

Fig4 Patient 2 Journey

Exploring blood biomarkers for monitoring COVID-19 disease progression and outcomes and impact of SARS-CoV-2 variants of concern

In April 2020, the Royal College of Pathologists published recommendations for  a set of blood COVID-19 biomarkers to monitor disease severity and progression, which have since been employed by many UK hospital diagnostics services. Subsequent findings regarding biomarkers and their ability to distinguish or predict severe disease remain under investigation and emerging evidence highlights that […]