Clinical laboratory International (CLI)
The leading international magazine for Clinical laboratory Equipment for everyone in the in vitro diagnostics field and related disciplines.
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panglobal2025-04-22 14:38:082025-04-22 14:39:07Beckman Coulter launches first modular spectral flow cytometry solution
Deep quantitative glycoprofiling: new method for fast, sensitive and in-depth mass spectrometry of protein glycosylation
, /in Protein Analysis, Proteomics & Mass Spectrometry, Featured Articles /by panglobalWhat is protein glycosylation? There are several types of post-translational modifications (PTMs) that proteins can undergo. Phosphorylation, methylation and acetylation all involve the addition of small chemical groups which affect function. Ubiquitylation involves the addition of the small peptide, ubiquitin, which targets proteins for degradation. Glycosylation is one of the more complex forms of PTM, […]
Prognostic value of circulating biomarkers in men compared to women presenting with acute chest pain
, /in Featured Articles, Cardiac Biomarkers /by panglobalby Dr Gard Myrmel We have known for a while now that the symptoms of acute coronary syndromes can be different for women compared to men. Here, Dr Myrmel discusses how the differences between the sexes also extend to the prognostic value of circulating biomarkers in patients presenting with acute chest pain.
Macrotroponin: potential source of cardiac troponin assay interference
, /in Cardiac Biomarkers, Featured Articles /by panglobalby PD Dr Angelika Hammerer-Lercher Measurement of cardiac-specific troponin I or T forms is part of the diagnostic pathway to rule in or rule out acute coronary syndromes, such as heart attack, as well as for prognostication of future cardiovascular disease. CLI chatted to Dr Angelika Hammerer-Lercher (Chief Physician and Director of Central Medical Laboratories, […]
Impact of glycosylation on NT-proBNP immunoassay performance
, /in Featured Articles, Cardiac Biomarkers /by panglobalby Dr Aleksandra Havelka Assays for NT-proBNP form a key part of diagnosing/ruling out, predicting and managing heart failure. CLI chatted to Dr Aleksandra Havelka (Gentian Diagnostics) to find out more about the challenges and limitations of measuring NT-proBNP concentrations, particularly the effects of glycosylation, and what developments are on the horizon to overcome these […]