Clinical laboratory International (CLI)

The leading international magazine for Clinical laboratory Equipment for everyone in the in vitro diagnostics field and related disciplines.

CLi Cover oct 2026

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Featured Articles

Hormone tests for diagnosis and therapeutic monitoring of growth hormone deficiency and acromegaly

by Dr Jacqueline Gosink Growth hormone (GH), insulin like growth factor I (IGF 1) and IGF binding protein 3 (IGFBP 3) are central regulators of growth and metabolism. Measurement of these biomarkers supports the diagnosis of growth disorders such as GH deficiency in children and acromegaly in adults. The analytes also play an important role […]

Urine biomarkers detect sarcopenia

Sarcopenia has a big impact on health as we age – and it’s not just about the risk of falls. It is estimated to affect 10–16% of the aging population but challenges with diagnosis mean that this is likely to be an underestimate. Current methods of analysing muscle all have limitations associated with them. CLI […]

Pharmacodynamic assessment of MET tyrosine kinase activation in tumour cells could aid personalized cancer treatment

Abnormal MET presence and activity are known to drive tumour growth, persistence and spread. However, although some patients respond well to current therapies many do not, which indicates that there are subtleties about the analysis of MET as a biomarker that have not been adequately analysed to date. CLI chatted with Dr Tony Navas (AbbVie, […]

Quantitative tandem mass tag-based proteomics allows biomarker analysis for Duchenne muscular dystrophy disease progression and therapeutic response assessment

Duchenne muscular dystrophy is a devastating progressive muscle disease that causes loss of ambulation by age 12 and premature death in early thirties. New gene therapy approaches are extending life span, but the physical assessments currently used make disease progression and therapy monitoring challenging, if not impossible. CLI chatted with Professor Yetrib Hathout and Ahmed […]

E-News

AI-designed molecules inhibit human enzyme exploited by HIV-1 and SARS-CoV-2

Korea University researchers have benchmarked 13 prediction models and 10 molecule-generation methods against a human enzyme that viruses exploit, then tested six AI-designed compounds in the laboratory. All three predicted-active compounds inhibited the enzyme and all three predicted-inactive compounds did not, though the researchers stress that the hits are early-stage fragments rather than drug candidates, […]

Beckman Coulter Diagnostics appoints Catherine Jennings as President

Beckman Coulter Diagnostics, a Danaher company, has appointed Catherine “Cat” Jennings as President. In the role, Jennings will lead the company’s strategic, operational and organisational priorities, applying a culture of continuous improve-ment to accelerate innovation, strengthen global impact and help laboratories and clinicians deliver better patient outcomes.

Mursla Bio publishes peer- reviewed validation of tissue- specific extracellular vesicle platform for liquid biopsy

Mursla Bio, a precision medicine and diagnostics company built on tissue-specific extra­cellular vesicles (TS-EVs), has announced publication of a peer-reviewed study in the Journal of Extracellular Vesicles [1] (impact factor 21.7), the founding journal of the International Society for Extracellular Vesicles. The company says the paper validates its TS-EV platform for a new class of […]

EVerZom completes preclinical studies needed to support clinical trial application for Crohn’s fistula candidate

EVerZom, a French biotechnology company specialising in exosome-based therapies for regenerative medicine, has completed the preclinical safety and biodistribution studies needed to support a clinical trial application (CTA) for its drug candidate EVerGel™. The company says the results confirm a favourable profile for further clinical development, and it aims to achieve first-in-human administration by the […]

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