Clinical laboratory International (CLI)

The leading international magazine for Clinical laboratory Equipment for everyone in the in vitro diagnostics field and related disciplines.

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Featured Articles

Hormone tests for diagnosis and therapeutic monitoring of growth hormone deficiency and acromegaly

by Dr Jacqueline Gosink Growth hormone (GH), insulin like growth factor I (IGF 1) and IGF binding protein 3 (IGFBP 3) are central regulators of growth and metabolism. Measurement of these biomarkers supports the diagnosis of growth disorders such as GH deficiency in children and acromegaly in adults. The analytes also play an important role […]

Urine biomarkers detect sarcopenia

Sarcopenia has a big impact on health as we age – and it’s not just about the risk of falls. It is estimated to affect 10–16% of the aging population but challenges with diagnosis mean that this is likely to be an underestimate. Current methods of analysing muscle all have limitations associated with them. CLI […]

Pharmacodynamic assessment of MET tyrosine kinase activation in tumour cells could aid personalized cancer treatment

Abnormal MET presence and activity are known to drive tumour growth, persistence and spread. However, although some patients respond well to current therapies many do not, which indicates that there are subtleties about the analysis of MET as a biomarker that have not been adequately analysed to date. CLI chatted with Dr Tony Navas (AbbVie, […]

Quantitative tandem mass tag-based proteomics allows biomarker analysis for Duchenne muscular dystrophy disease progression and therapeutic response assessment

Duchenne muscular dystrophy is a devastating progressive muscle disease that causes loss of ambulation by age 12 and premature death in early thirties. New gene therapy approaches are extending life span, but the physical assessments currently used make disease progression and therapy monitoring challenging, if not impossible. CLI chatted with Professor Yetrib Hathout and Ahmed […]

E-News

Inceptua Group acquires SupplyRx to expand pharmacy services for clinical trials

Inceptua Group, a provider of clinical trial supply, related services and early access programmes, has acquired SupplyRx, Inc., a US-based company offering cloud-based digital tools for clinical trial pharmacy programmes in the US and Canada. Inceptua is backed by Vesey Street Capital Partners, and financial terms were not disclosed.

Big Picture Bio launches with £1.5 million to design cancer combination therapies

London-based Big Picture Bio Ltd has been founded to identify, design and optimise cancer combination therapies. It uses a generative world model of how tumours, immune cells and surrounding tissue interact across disease sites and patient subgroups. The company, which announced its launch on 17 September 2026, pairs AI-driven modelling with targeted wet lab validation. […]

Watermarks in AI-designed proteins preserve binding in laboratory tests

Google DeepMind scientists have embedded detectable provenance watermarks in AI-designed protein binders and in AlphaFold 3 biomolecular structure predictions. Surface plasmon resonance measurements showed that watermarked binders bound three therapeutically relevant targets with affinity comparable with unmarked designs, although the authors caution that the sequence watermark can be removed and that the approach remains only […]

Dried blood protocol detects Zika and hepatitis C RNA without laboratory equipment

A new dried whole blood protocol allows Zika virus and hepatitis C virus RNA to be amplified and detected without extraction, purification or a centrifuge. Using a portable heater and a low-cost, palm-sized fluorescence reader, University of Illinois Urbana-Champaign researchers detected both viruses at low concentrations in whole blood, with the workflow taking around two […]

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