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Therapeutic drug monitoring of favipiravir, a potential COVID-19 drug candidate

The COVID-19 outbreak caused by severe acute respiratory syndrome virus 2 (SARS-CoV-2) that was declared a pandemic in March 2020 has resulted in a the development of diagnostic tests and vaccines at an unprecedented speed. The development of de novo therapeutics, though, takes considerably longer, which is where the repurposing of existing drugs is being […]

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How the COVID-19 response was informed by – and informs – our battle against other global health crises

The COVID-19 pandemic has reinforced the critical importance of diagnosis and access to these services, both at the individual and at a population level. The pandemic has also impacted the delivery of diagnostics and care for other medical conditions, such as HIV/AIDS, but similarly, lessons learned with COVID-19 can also be applied to improve diagnostic […]

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Colorimetric histology: benefits, opportunities and future directions

Despite rapid advances in the areas of genomics and digital image analysis, cancer diagnosis remains largely reliant on tissue/cellular morphological assessment by an expert pathologist. Here, we summarize a newly developed approach to histology, based on a plasmon-induced colour change which provides instant, label-free visualization (or contrast) of cancer cells, distinguishing them from other cells […]

vegan food

Researchers sound warning on vitamin B12 deficiency for people following plant-based diets

Leading researchers are warning of the dangers of a quiet epidemic of vitamin B12 deficiency in people who follow increasingly popular plant-based diets and explain how it can be addressed.

microsplastics

People with IBD have more microplastics in their faeces, study finds

Microplastics – tiny pieces of plastic less than 5 mm in length – are everywhere, from bottled water to food to air. They have been found in the deepest part of the ocean and the top of Mount Everest. According to recent estimates, people consume tens of thousands of these particles each year, with unknown […]

vaccine

Immune system-stimulating nanoparticle could lead to more powerful vaccines

A common strategy to make vaccines more powerful is to deliver them along with an adjuvant – a compound that stimulates the immune system to produce a stronger response.

3d brain synapses

Researchers create mind-blowing tool to visualise millions of neuronal synapses in mouse brain

To solve the mysteries of how learning and memory occur, Johns Hopkins Medicine scientists have created a system to track millions of connections among brain cells in mice – all at the same time – when the animals’ whiskers are tweaked, an indicator for learning.

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Ziath introduces new versatile low light barcode reader

Ziath has introduced Cyclops – a new linear and 2D barcode reader for its popular DataPaq Mirage, Cube and Express rack readers.

porvair580

Robust, reproducible sample preparation for LC/MS

Porvair Sciences has published an in-depth application report demonstrating how their Microlute CP Reverse Phase Solid Phase Extraction (SPE) microplates provide a robust and highly reproducible SPE LC-MS sample preparation methodology for a range of neutral, acidic, and basic analytes.

SIRIX

Isotopx’s new SIRIX offers new standard in high performance isotope ratio mass spectrometry

Isotopx, a British scientific instrument manufacturing company specialising in the design and manufacture of world class isotope ratio mass spectrometers, has launched SIRIX, a new large radius gas source stable isotope ratio mass spectrometer.