Latest issue of Clinical laboratory
November 2025
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Tissue dissection: the missing link in modern molecular pathology
, /in Featured Articles /by panglobalHistopathology has benefitted hugely from the digitization of whole slide imaging, allowing remote discussions (telepathology), image archiving which facilitates storage and retrieval, comparison of areas on different slides, and direct slide annotation. However, until recently, the selection of tissue from the slide for further downstream molecular analysis has still been a time-consuming, manual process. This […]
Bridging the omics gap: From clinical research to pathology
, /in Featured Articles /by panglobalMatrix-assisted laser desorption/ionization (MALDI) imaging is a technique that is on the cusp of revolutionizing histopathology. This article discusses the benefits of MALDI imaging and how it is beginning to be used in oncology, with particular relevance to the challenging area of lipid analysis.
IL-6 and identification of patients most at risk of severe COVID complications
, /in Featured Articles /by panglobalDuring the course of the last 18 months, we have learned a lot about COVID-19, which was a new disease. It became apparent early on that one outcome of severe COVID-19 was acute respiratory distress syndrome (ARDS), with patients usually requiring mechanical ventilation. CLI caught up with Dr Anagh Vora (Senior Vice President and Chief […]
Anti-Müllerian hormone as a biochemical marker of gonadal development and fertility status
, /in Featured Articles /by panglobalAnti-Müllerian hormone (AMH) plays a critical role in sex differentiation in fetal development and goes on to be important in the regulation of folliculogenesis in women. This article discusses the role of AMH in reproductive physiology and the many different situations where assessment of AMH levels is useful, as well as touching on methods of […]
The only glucose meter cleared by the U.S. FDA for use with critically ill patients
, /in Advertenties /by Nova Biomedical Corp.Dip&Spin® Urinalysis Dipstick & Microscopics Control
, /in Advertenties /by panglobalResearchers use exosome-based strategy to block HIV in mice
, /in E-News /by panglobalIn a new study, researchers used exosomes to deliver novel protein into the cells of mice infected with HIV. The protein attached to HIVs’ genetic material and prevented itfrom replicating, resulting in reduced levels of HIV in the bone marrow, spleen, and brain. The study, funded by the US NIH’s National Institute of Mental Health […]
University of Oxford, Oracle’s Global Pathogen Analysis System help researchers identify COVID-19 variants faster
, /in E-News /by panglobalThe fast spread of the highly infectious Delta variant underscores the need for faster identification of COVID-19 mutations. Uniting governments and medical communities in this challenge, the University of Oxford and Oracle’s Global Pathogen Analysis System (GPAS) is now being used by organizations on nearly every continent.
Regulator proteins or symphonies of genes: Statistical modelling points way to unified theory for DNA folding
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Machine learning assisted protein structure analysis reveals SARS-CoV-2 virus tactics
, /in E-News /by panglobalHow does the SARS-CoV-2 virus manage to evade immune defence and replicate itself in patients suffering from COVID-19? To shed light on this question, an internationalresearch team has assembled the most comprehensive view to date on the precise, three-dimensional shape of each SARS-CoV-2 protein – including the well-known spike protein.