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Novel home finger-prick blood test detects Alzheimer’s disease pathology

A groundbreaking international study has demonstrated that Alzheimer’s disease biomarkers can be accurately detected using simple finger-prick blood samples collected at home and posted to laboratories without refrigeration. The DROP-AD project, involving 337 participants across seven European centres, found that capillary blood spots could measure key markers including phosphorylated tau 217 (p-tau217) with 86% accuracy […]

pangenomics at scale

New data compression technique transforms pangenomics research

Researchers at UC San Diego have developed PanMAN, a novel data structure that compresses pangenomic information up to 1,391 times more efficiently than existing formats whilst simultaneously encoding detailed evolutionary and mutational histories. The technique, published in Nature Genetics, enabled construction of a comprehensive SARS-CoV-2 pangenome from 8 million sequences using just 366 MB of […]

MUTE Seq

Korean researchers develop ultra-precise CRISPR technique that dramatically improves detection of rare cancer mutations

Researchers have engineered a highly accurate CRISPR variant that removes normal DNA before sequencing, enabling detection of circulating tumour DNA at levels as low as 0.005%. The MUTE-Seq method showed promising results in early-stage lung and pancreatic cancer patients, where conventional liquid biopsy often fails.

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Revvity unveils AI platform for molecular discovery

Revvity has announced the launch of Signals Xynthetica, a Models-as-a-Service AI platform designed to accelerate molecular and materials discovery by integrating computational design with experimental validation within a unified environment.

touchlight

Touchlight launches circular DNA architectures for gene therapy

Touchlight has expanded its mbDNA (megabulb DNA) platform with three new circular DNA architectures designed to enhance gene editing and therapeutic development. The company says that sscDNA, hsscDNA, and dscDNA constructs now complement its existing mbDNA technology, offering researchers customisable solutions for gene insertion and expression applications.

epicycpher

EpiCypher introduces cloud-based epigenomic analysis platform

EpiCypher has launched CUTANA Cloud, a bioinformatics platform designed to streamline the analysis of chromatin mapping assays including CUT&RUN, CUT&Tag, and future applications such as ATAC-seq. Built on the DNAnexus precision health platform, the system aims to reduce the time required for researchers to process epigenomic data from weeks to hours.

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AFYS3G unveils Lambda768 laser marking system

AFYS3G has launched the Lambda768 Information Marking System, a laser marking solution designed to enhance sample traceability in clinical and research laboratories. The system processes up to 500 tubes per hour across multiple rack formats, addressing the growing demand for efficient sample identification in high-throughput environments.

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Abselion launches His-tagged protein quantification kit

Cambridge-based life sciences technology company Abselion has expanded its Amperia assay portfolio with the launch of a His-tagged protein quantification kit and sensor strips, developed in collaboration with GenScript. The new product offers researchers a ready-to-use solution for rapid measurement of His-tagged proteins in crude and purified samples.

SGS Clinical Pharmacology Unit

SGS unveils RSV A-strain challenge agent for vaccine research

SGS has launched a novel Respiratory Syncytial Virus (RSV) A-strain challenge agent designed to accelerate clinical validation of RSV vaccines and therapeutics through controlled human infection models (CHIM).

Torrey Pines HS19

Torrey Pines Scientific launches corrosion resistant hot plates

Torrey Pines Scientific, Inc. has announced a new range of corrosion resistant multi-position stirring analog hot plates and stirrers designed for acid digestions and handling corrosive solutions in laboratory settings.