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Fruit fly brain connectome: A landmark achievement in neuroscience

In a significant advancement for neuroscience, researchers have successfully mapped nearly 140,000 neurons in the brain of a common fruit fly, creating the largest and most complete connectome of an adult animal to date. This groundbreaking work, supported by the U.S. National Institutes of Health (NIH), provides a detailed wiring diagram of the fruit fly […]

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Pitfalls and challenges in the diagnosis of acid–base disorders by blood gas analysis

Blood gas analysis for the diagnosis of acid–base disorders is now mainly performed at the point-of-care and the results reported can be affected by a number of factors. Users should be aware of the possible pitfalls to prevent errors in diagnosis and to optimize patient management. CLI chatted to Dr Kate Shipman (Consultant Chemical Pathologist, […]

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Impact of analyte stability on the urine analysis of porphyrins and their precursors

In a previous article (CLI October 2021 “Diagnosis of acute hepatic porphyria”), we discussed in detail the biochemistry and the diagnosis of the different types of porphyria. Here, we give a brief recap before going on to discuss a recent paper by Gallagher et al. that examined the effects of different specimen storage and handling […]

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TTF-1 expression may be a useful indicator of improved survival in non-small cell lung cancer patients

According to the most recent statistics provided by Cancer Research UK, lung cancer is the third most common cancer in the UK, with around 49 000 new cases in the UK every year which account for 13% of all new cancer cases.

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Analysis of triple-negative breast cancer samples reveals new markers that may aid diagnosis and ultimately treatment

Breast cancer is the most common cancer in females in the UK, with around 56 800 new cases diagnosed every year.

TestaAnalytical Prep Flowmeter

New flow monitoring device aims to enhance preparative HPLC efficiency

Continuous flow rate measurement for improved fraction purity and yield

Vapourtec

Vapourtec launches specialised UV detector for peptide synthesis and flow chemistry

New device aims to enhance efficiency in pharmaceutical research and development

Micronic EFC Refill Rack

Micronic introduces sustainable sample storage solution

New refill rack system aims to reduce laboratory waste

Sphere Fluidics CMChroma

Sphere Fluidics unveils next-generation single-cell analysis platform

Cambridge-based Sphere Fluidics has announced the development of Cyto-Mine Chroma, an advanced iteration of its Cyto-Mine platform for single-cell analysis and isolation. Set to launch in Q1 2025, the new system aims to enhance workflow efficiency in biotherapeutic discovery and development.

BioRad Vericheck

Bio-rad launches new ddPCR kit for AAV vector characterisation

Vericheck ddPCR Empty-Full Capsid Kit aims to enhance gene therapy development