Latest issue of Clinical laboratory
November 2025
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Mapping, monitoring and surveillance of Tropical and Neglected Diseases
, /in Advertenties /by panglobalTropical infectious diseases such as malaria, cholera, yellow fever, and Dengue affect more than 2 billion people worldwide. Also included in this list are the so-called “Neglected Tropical Diseases” or NTD’s, a sub-group of mainly infectious diseases that occur against a background of extreme poverty. The WHO lists 17 priority Neglected Tropical Diseases, among them […]
A Breakthrough in Hemostasis Quality Management
, /in Advertenties /by panglobalExtending standardization beyond the analytical phase
Researchers develop nano- pillars to breach cell nuclei without damage
, /in E-News /by panglobalResearchers at the University of California San Diego have developed an innovative nanotechnology that can create temporary openings in the nuclear membrane of living cells without damaging the cell’s outer structure. This breakthrough, published in the journal Advanced Functional Materials [1], could revolutionize gene therapy and drug delivery methods by providing direct access to the […]
Artificial cell nuclei created in living mouse eggs
, /in E-News /by panglobalResearchers from Kindai University and collaborating institutions have achieved a significant milestone in cell biology by creating artificial cell nuclei within living mouse eggs. The study, published in the journal Genes to Cells [1], demonstrates for the first time that functional nuclei can be constructed by injecting purified DNA solution into oocytes, mimicking the fertilisation […]
Fruit fly brain connectome: A landmark achievement in neuroscience
, /in E-News /by panglobalIn a significant advancement for neuroscience, researchers have successfully mapped nearly 140,000 neurons in the brain of a common fruit fly, creating the largest and most complete connectome of an adult animal to date. This groundbreaking work, supported by the U.S. National Institutes of Health (NIH), provides a detailed wiring diagram of the fruit fly […]
Pitfalls and challenges in the diagnosis of acid–base disorders by blood gas analysis
, /in Featured Articles /by panglobalBlood gas analysis for the diagnosis of acid–base disorders is now mainly performed at the point-of-care and the results reported can be affected by a number of factors. Users should be aware of the possible pitfalls to prevent errors in diagnosis and to optimize patient management. CLI chatted to Dr Kate Shipman (Consultant Chemical Pathologist, […]
Impact of analyte stability on the urine analysis of porphyrins and their precursors
, /in Featured Articles, Urine Analysis /by panglobalIn a previous article (CLI October 2021 “Diagnosis of acute hepatic porphyria”), we discussed in detail the biochemistry and the diagnosis of the different types of porphyria. Here, we give a brief recap before going on to discuss a recent paper by Gallagher et al. that examined the effects of different specimen storage and handling […]
TTF-1 expression may be a useful indicator of improved survival in non-small cell lung cancer patients
, /in Featured Articles, Tumour Markers /by panglobalAccording to the most recent statistics provided by Cancer Research UK, lung cancer is the third most common cancer in the UK, with around 49 000 new cases in the UK every year which account for 13% of all new cancer cases.