The MiniBeadbeater-24 cell disrupter disrupts and homogenizes all cell types, from bacteria and spores to animal and plant tissues. Cell lysis takes place in sealed 2 ml microvials containing glass or ceramic beads. Nucleic acids and proteins are isolated in 1-2 minutes of bead beating. The ultra-high energy shaking machine processes up to 24 samples, has variable speed for special applications and simple controls. Essential for PCR methodologies, the MiniBeadbeater-24 uses disposable vials and beads, thus eliminating any possibility of cross-contamination between samples.
LABGEO HC10 is a fast and easy to use 3-part WBC differential automated hematology analyser offering an optimal solution for clinics and practices. This analyser delivers reliable & accurate results within 45 seconds to enable rapid diagnosis and increase patient satisfaction. Also with a simple three-step testing process and the use of automated sample loader, this device is easy to use and prevents contamination.
Cystatin C high quality reagent, from Randox Laboratories
Cystatin C is a small cysteine proteinase inhibitor produced at a constant rate by all nucleated cells. The small molecular weight of Cystatin C allows it to be removed and completely broken down by the kidneys.
Advantages of Cystatin C over Creatinine include:
It is virtually unaffected by non-renal factors, such as muscle, mass, weight, height or age;
Highly sensitive to small changes in GFR;
Can be used to monitor renal function in individuals with liver disease.
The Randox Cystatin C reagent is suitable for both serum and plasma samples; liquid ready-to-use, offers excellent precision and has a wide measuring range allowing normal and abnormal values to be measured without any additional dilution.
https://clinlabint.com/wp-content/uploads/sites/2/2020/08/randox-Week-2-Image.jpg1501363wmediahttps://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png3wmedia2020-08-26 09:19:532021-01-08 11:28:57Cystatin C Reagent
The Active-B12 assay from Axis-Shield provides an innovative and highly accurate method for assessing Vitamin B12 status and is now available in the USA. The Axis-Shield assay measures Holotranscobalamin, the bio-active form of the vitamin. Holotranscobalamin represents only 10-30% of circulating B12 but is the only form taken up and utilised by the cells of the body – the Active-B12 assay therefore gives a more accurate assessment of the body’s B12 status. The use of a specific monoclonal antibody for Holotranscobalamin means that the assay does not suffer from the interference from anti-Intrinsic Factor antibodies which can be a medically serious failing of some traditional Vitamin B12 testing methods. The Axis-Shield Active-B12 assay is a standard 96-well ELISA with break-apart strips and is supplied with all required reagents, calibrators and controls. The kit is compatible with liquid-handling automates for higher throughput. Read more
https://clinlabint.com/wp-content/uploads/sites/2/2020/08/C346a_AxisShield_FMABT100_1.jpg1001503wmediahttps://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png3wmedia2020-08-26 09:19:222021-01-08 11:28:44Active-B12 now available in USA
The Neonatal Biotinidase Screening Assay is an enzymatic assay for the quantitative determination of biotinidase activity in neonates using blood spot samples dried on Whatman S&S 903 filter collection paper. A non-invasive sampling method is used where specimens are collected by applying a few drops of blood freshly drawn from the infant’s heel with a lancet onto specially manufactured absorbent specimen collection (filter) paper. This method has many advantages: short collection time, low invasiveness, reduction of sample volume and ease of sample storage. It allows quantitative results to minimize the needs of a confirmatory test. Convenient transport and good stability of the samples and ready to use reagents are assured. Read more
A multiparametric indirect immunofluorescence assay (IFA) for the simultaneous detection of infections with different old and new world hantaviruses has been developed and evaluated in an international study published in PLOS Neglected Tropical Diseases in April 2013. The IFA utilizes BIOCHIP Mosaics, with each substrate consisting of cells infected with one of the virus types Hantaan (HTNV), Puumala (PUUV), Seoul (SEOV), Saaremaa (SAAV), Dobrava (DOBV), Sin Nombre (SNV) or Andes (ANDV). In the evaluation study, 184 confirmed seropositive sera from six diagnostic centres worldwide and 89 control sera were analysed for specific antibodies of immunoglobulin classes IgG and IgM against hantaviruses using the IFA. The assay demonstrated an overall sensitivity of 100% for all serotypes with the exception of SNV (96%) and an overall specificity of at least 98% for each serotype. 99% of the patient sera exhibited IgG antibodies and 71% IgM antibodies. Notably, the IFA was able to distinguish PUUV and ANDV infections from those with murinae-borne hantaviruses such as DOBV and SEOV, thus providing useful additional information for therapeutic decision making. The authors note that many hantavirus patients are still clinically misdiagnosed as having influenza-like infections, renal failure or idiopathic acute respiratory distress syndrome. Accurate diagnosis is, however, essential given the mortality rates of up to 35% from hantavirus syndromes. The misdiagnosis rate combined with the increasing number of hantavirus infections worldwide demonstrates the need for simple and reliable tests which allow detection of all clinically relevant hantavirus serotypes. Analysis of specific antibodies is the method of choice for diagnosing hantavirus infections. By combining the most important pathogenic hantaviruses in one assay, this IFA system is suited to detect any hantaviral infection worldwide. The test is particularly suitable for serodiagnostic screening in regions where multiple serotypes are endemic. Read more
https://clinlabint.com/wp-content/uploads/sites/2/2020/08/C342_Euroimmun_PUUV_IgG-pos-1.jpg1191503wmediahttps://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png3wmedia2020-08-26 09:19:222021-01-08 11:28:44Multiparametric immunofluorescence assay for hantaviruses
The OSOM® RSV/Adeno Test provides differential diagnosis for respiratory syncytial virus (RSV) and/or Adenovirus within 10 minutes with good sensitivity versus PCR (>90% RSV; 85% versus Adenovirus). Sample types include nasal swabs, nasal suction fluid or throat swabs (for Adenovirus). Features include objective, two colour results and room temperature storage. Read more
https://clinlabint.com/wp-content/uploads/sites/2/2020/08/C350_Sekisui_RSVAdeno.jpg1181503wmediahttps://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png3wmedia2020-08-26 09:19:222021-01-08 11:28:44RSV/Adenovirus differential test
A new strip-based test for quick and easy hemoglobin analysis for anemia determination is now available. STAT-Site M Hgb is a pocket-sized device that reliably delivers accurate hemoglobin analysis results within 30 seconds from 15 μL of finger-prick whole blood. This hemoglobin photometer is maintenance-free, and features intuitive, step by step on-screen instructions minimize training and ensure ease of use. Due to its durability, portability and userfriendliness, STAT-Site M Hgb is especially suited to blood screening programmes in developing world markets, but it also has a niche in settings where operators are mobile. Using just one 3V Li type battery for every 1,000 tests and with an operating temperature range of 16° to 35°C, the analyser is ideal for field use. Read more
https://clinlabint.com/wp-content/uploads/sites/2/2020/08/C340_EKF_Stat-Site-M-Hgb-Analyser.jpg1501253wmediahttps://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png3wmedia2020-08-26 09:19:222021-01-08 11:28:43Strip-based test for hemoglobin
Part of the company’s Hemato- Flow solution combining diagnostic reagent, hematology and flow cytometry hardware and IT expertise, Version 2 CytoDiff CXP Autogating software is designed to give laboratories added confidence in the use of flow cytometry in the routine hematology lab for the auto-validation of abnormal samples. Easy-to-use, the advanced Version 2 software further improves sub-population classifications. It adds new features, such as greater precision in the removal of potential interference and metrics that provide a new ‘confidence level’ on population classification. The new software simplifies the review process making it easier to validate results with greater certainty. HematoFlow with the CytoDiff five-colour antibody cocktail and CXP Autogating Software make it possible to use the precision of flow cytometry to deliver extended white blood cell (WBC) differential results with far greater consistency than manual microscopic assessment. The five-colour antibody cocktail, the CytoDiff, uses six monoclonal antibodies to establish the differential. The routine use of flow cytometry for validating abnormal samples can improve workflow and turnaround time as well as providing access to additional diagnostic information for patients. European laboratories are already working with Beckman Coulter to increase confidence in the routine use of flow cytometry in the hematology process for validating abnormal samples. Hospitals including University Hospital, Rennes and Bordeaux in France, Erasme University Hospital, Brussels, Belgium and several private labs are successfully adopting this approach. CytoDiff is not available for in vitro diagnostic use in the United States and other geographies. Read more
https://clinlabint.com/wp-content/uploads/sites/2/2020/08/C347_Beckman_CytoDiff-Panel-Kit-OL.jpg1061503wmediahttps://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png3wmedia2020-08-26 09:19:222021-01-08 11:28:43Flow cytometry software for hematology
The reliable stabilization of blood sugar levels directly after sampling is an important precondition for the accuracy of the analysis results. VACUETTE® GLUCOMEDICS was specially developed for this application. The additive mixture in the tube stabilizes the blood sample immediately after sampling and thus impedes the breakdown of glucose over time (glycolysis). The combination of sodium EDTA, sodium fluoride, citric acid and sodium citrate acidifies the whole blood sample, resulting in the immediate and complete inhibition of glycolysis, thus setting it apart from conventional sodium fluoride tubes. The glucose concentration of whole blood and/or plasma samples is kept constant at room temperature for up to 48 hours at the “in-vivo value” (almost 100% of the original value). The dosed liquid additives ensure the easy mixing of the additive with the whole blood sample. To make up for the dilution effect of the additive, the analysis result must be multiplied by 1.16. This is required to obtain the “in-vivo glucose concentration” in the plasma. Read more
https://clinlabint.com/wp-content/uploads/sites/2/2020/08/C349_GreinerBioOne_Glucomedics_280313_00002_l.jpg1211503wmediahttps://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png3wmedia2020-08-26 09:19:222021-01-08 11:28:43Sampling tube for effective glycolysis inhibition
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Multisample cell disrupter
, /in Product News /by 3wmediaThe MiniBeadbeater-24 cell disrupter disrupts and homogenizes all cell types, from bacteria and spores to animal and plant tissues. Cell lysis takes place in sealed 2 ml microvials containing glass or ceramic beads. Nucleic acids and proteins are isolated in 1-2 minutes of bead beating. The ultra-high energy shaking machine processes up to 24 samples, has variable speed for special applications and simple controls. Essential for PCR methodologies, the MiniBeadbeater-24 uses disposable vials and beads, thus eliminating any possibility of cross-contamination between samples.
For more information please click here
Read more
Hematology analyser
, /in Product News /by 3wmediaLABGEO HC10 is a fast and easy to use 3-part WBC differential automated hematology analyser offering an optimal solution for clinics and practices. This analyser delivers reliable & accurate results within 45 seconds to enable rapid diagnosis and increase patient satisfaction. Also with a simple three-step testing process and the use of automated sample loader, this device is easy to use and prevents contamination.
Read more
Cystatin C Reagent
, /in Product News /by 3wmediaCystatin C high quality reagent, from Randox Laboratories
Cystatin C is a small cysteine proteinase inhibitor produced at a constant rate by all nucleated cells. The small molecular weight of Cystatin C allows it to be removed and completely broken down by the kidneys.
Advantages of Cystatin C over Creatinine include:
The Randox Cystatin C reagent is suitable for both serum and plasma samples; liquid ready-to-use, offers excellent precision and has a wide measuring range allowing normal and abnormal values to be measured without any additional dilution.
Website: http://www.randox.com/clinical-chemistry-reagents.php
Email: marketing@randox.com
Read more
Active-B12 now available in USA
, /in Product News /by 3wmediaThe Active-B12 assay from Axis-Shield provides an innovative and highly accurate method for assessing Vitamin B12 status and is now available in the USA. The Axis-Shield assay measures Holotranscobalamin, the bio-active form of the vitamin. Holotranscobalamin represents only 10-30% of circulating B12 but is the only form taken up and utilised by the cells of the body – the Active-B12 assay therefore gives a more accurate assessment of the body’s B12 status. The use of a specific monoclonal antibody for Holotranscobalamin means that the assay does not suffer from the interference from anti-Intrinsic Factor antibodies which can be a medically serious failing of some traditional Vitamin B12 testing methods. The Axis-Shield Active-B12 assay is a standard 96-well ELISA with break-apart strips and is supplied with all required reagents, calibrators and controls. The kit is compatible with liquid-handling automates for higher throughput.
Read more
Biotinidase neonatal screening
, /in Product News /by 3wmediaThe Neonatal Biotinidase Screening Assay is an enzymatic assay for the quantitative determination of biotinidase activity in neonates using blood spot samples dried on Whatman S&S 903 filter collection paper. A non-invasive sampling method is used where specimens are collected by applying a few drops of blood freshly drawn from the infant’s heel with a lancet onto specially manufactured absorbent specimen collection (filter) paper. This method has many advantages: short collection time, low invasiveness, reduction of sample volume and ease of sample storage. It allows quantitative results to minimize the needs of a confirmatory test. Convenient transport and good stability of the samples and ready to use reagents are assured.
Read more
Multiparametric immunofluorescence assay for hantaviruses
, /in Product News /by 3wmediaA multiparametric indirect immunofluorescence assay (IFA) for the simultaneous detection of infections with different old and new world hantaviruses has been developed and evaluated in an international study published in PLOS Neglected Tropical Diseases in April 2013. The IFA utilizes BIOCHIP Mosaics, with each substrate consisting of cells infected with one of the virus types Hantaan (HTNV), Puumala (PUUV), Seoul (SEOV), Saaremaa (SAAV), Dobrava (DOBV), Sin Nombre (SNV) or Andes (ANDV). In the evaluation study, 184 confirmed seropositive sera from six diagnostic centres worldwide and 89 control sera were analysed for specific antibodies of immunoglobulin classes IgG and IgM against hantaviruses using the IFA. The assay demonstrated an overall sensitivity of 100% for all serotypes with the exception of SNV (96%) and an overall specificity of at least 98% for each serotype. 99% of the patient sera exhibited IgG antibodies and 71% IgM antibodies. Notably, the IFA was able to distinguish PUUV and ANDV infections from those with murinae-borne hantaviruses such as DOBV and SEOV, thus providing useful additional information for therapeutic decision making. The authors note that many hantavirus patients are still clinically misdiagnosed as having influenza-like infections, renal failure or idiopathic acute respiratory distress syndrome. Accurate diagnosis is, however, essential given the mortality rates of up to 35% from hantavirus syndromes. The misdiagnosis rate combined with the increasing number of hantavirus infections worldwide demonstrates the need for simple and reliable tests which allow detection of all clinically relevant hantavirus serotypes. Analysis of specific antibodies is the method of choice for diagnosing hantavirus infections. By combining the most important pathogenic hantaviruses in one assay, this IFA system is suited to detect any hantaviral infection worldwide. The test is particularly suitable for serodiagnostic screening in regions where multiple serotypes are endemic.
Read more
RSV/Adenovirus differential test
, /in Product News /by 3wmediaThe OSOM® RSV/Adeno Test provides differential diagnosis for respiratory syncytial virus (RSV) and/or Adenovirus within 10 minutes with good sensitivity versus PCR (>90% RSV; 85% versus Adenovirus). Sample types include nasal swabs, nasal suction fluid or throat swabs (for Adenovirus). Features include objective, two colour results and room temperature storage.
Read more
Strip-based test for hemoglobin
, /in Product News /by 3wmediaA new strip-based test for quick and easy hemoglobin analysis for anemia determination is now available. STAT-Site M Hgb is a pocket-sized device that reliably delivers accurate hemoglobin analysis results within 30 seconds from 15 μL of finger-prick whole blood. This hemoglobin photometer is maintenance-free, and features intuitive, step by step on-screen instructions minimize training and ensure ease of use. Due to its durability, portability and userfriendliness, STAT-Site M Hgb is especially suited to blood screening programmes in developing world markets, but it also has a niche in settings where operators are mobile. Using just one 3V Li type battery for every 1,000 tests and with an operating temperature range of 16° to 35°C, the analyser is ideal for field use.
Read more
Flow cytometry software for hematology
, /in Product News /by 3wmediaPart of the company’s Hemato- Flow solution combining diagnostic reagent, hematology and flow cytometry hardware and IT expertise, Version 2 CytoDiff CXP Autogating software is designed to give laboratories added confidence in the use of flow cytometry in the routine hematology lab for the auto-validation of abnormal samples. Easy-to-use, the advanced Version 2 software further improves sub-population classifications. It adds new features, such as greater precision in the removal of potential interference and metrics that provide a new ‘confidence level’ on population classification. The new software simplifies the review process making it easier to validate results with greater certainty. HematoFlow with the CytoDiff five-colour antibody cocktail and CXP Autogating Software make it possible to use the precision of flow cytometry to deliver extended white blood cell (WBC) differential results with far greater consistency than manual microscopic assessment. The five-colour antibody cocktail, the CytoDiff, uses six monoclonal antibodies to establish the differential. The routine use of flow cytometry for validating abnormal samples can improve workflow and turnaround time as well as providing access to additional diagnostic information for patients. European laboratories are already working with Beckman Coulter to increase confidence in the routine use of flow cytometry in the hematology process for validating abnormal samples. Hospitals including University Hospital, Rennes and Bordeaux in France, Erasme University Hospital, Brussels, Belgium and several private labs are successfully adopting this approach. CytoDiff is not available for in vitro diagnostic use in the United States and other geographies.
Read more
Sampling tube for effective glycolysis inhibition
, /in Product News /by 3wmediaThe reliable stabilization of blood sugar levels directly after sampling is an important precondition for the accuracy of the analysis results. VACUETTE® GLUCOMEDICS was specially developed for this application. The additive mixture in the tube stabilizes the blood sample immediately after sampling and thus impedes the breakdown of glucose over time (glycolysis). The combination of sodium EDTA, sodium fluoride, citric acid and sodium citrate acidifies the whole blood sample, resulting in the immediate and complete inhibition of glycolysis, thus setting it apart from conventional sodium fluoride tubes. The glucose concentration of whole blood and/or plasma samples is kept constant at room temperature for up to 48 hours at the “in-vivo value” (almost 100% of the original value). The dosed liquid additives ensure the easy mixing of the additive with the whole blood sample. To make up for the dilution effect of the additive, the analysis result must be multiplied by 1.16. This is required to obtain the “in-vivo glucose concentration” in the plasma.
Read more