Latest issue of Clinical laboratory
November 2025
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Immune cell profiling and circulating tumour cell analysis can aid risk stratification and personalized decision-making in newly diagnosed multiple myeloma patients
, /in Featured Articles, Hematology & Flow Cytometry /by panglobalWhat is multiple myeloma? Multiple myeloma (also called myeloma) is the over-proliferation of abnormal plasma cells (which normally make antibodies) in the bone marrow (Figs 1&2).
Simplify Your PBMC Isolation with EasySep™ Direct
, /in Advertenties /by panglobalAvoid the challenges of traditional PBMC isolation.
Albumin in Urine – precise and early detection of kidney dysfunction
, /in Product News /by panglobalChronic kidney disease (CKD) affects more than 850 million individuals worldwide and represents a major public health challenge. Despite its high prevalence, CKD is frequently underdiagnosed due to its asymptomatic nature and slow progression. Early detection is essential to prevent irreversible kidney damage and improve clinical outcomes. Urinary albumin is one of several markers used […]
KLoneus® Free Light Chain (FLC) assays, for Turdidimetry and Nephelometry
, /in E-News, Product News /by panglobalTRIMERO Diagnostics offers, under the brand KLoneus®, IVD CE marked nephelometric assays for testing FREE LIGHT CHAINS (FLC) on Beckman Coulter’s IMMAGE® Immunochemical Systems and Siemens’ BN™ nephelometric systems.
Early results suggest bile acids may be useful as diagnostic and prognostic markers for bone and muscle diseases
, /in Featured Articles, Protein Analysis, Proteomics & Mass Spectrometry /by panglobalHistorically, bile acids (BAs) were thought of as playing a role in lipid metabolism. In recent years, however, they have been found to affect the body in a much more wide-ranging way and are important in many normal functions and, therefore, also many disease states. CLI chatted to Dr Giovanny Rodriguez Blanco, lab leader at […]
United expertise for your allergy diagnostics
, /in Advertenties /by panglobalLet’s embark on a new journey together!
Albumin in Urine / CSF FS
, /in Advertenties /by panglobalPrecise and early detection of kidney dysfunction
Computational design reveals structural principles governing membrane protein stability
, /in Featured Articles /by panglobalScientists at Scripps Research have developed a computational approach for designing synthetic membrane proteins, uncovering critical atomiclevel interactions that govern protein folding and stability within cellular lipid environments. The methodology offers new insights into disease-related protein dysfunction and potential therapeutic targets. Membrane proteins constitute essential molecular machinery for cellular function, mediating substance transport, signal transmission, […]
Tyramide signal amplification allows analysis of single circulating tumour cells and extracellular vesicles from glioblastoma liquid biopsies
, /in Featured Articles, Tumour Markers /by panglobalBackground What are circulating tumour cells and extracellular vesicles? Circulating tumour cells (CTCs) are cancer cells that have been shed from a primary tumour into the bloodstream or lymphatic system. They are carried around the body and can be the seeds that form metastases. Extracellular vesicles (EVs) are tiny lipid-bilayer bound particles that are shed […]
Development of gender-specific thresholds in urine flow cytometry testing for urinary tract infection
, /in Featured Articles, Urine Analysis /by panglobalBackground A urinary tract infection (UTI) is an infection – usually bacterial – of any part of the urinary tract. Most commonly, a UTI would involve the lower urinary tract (urethra and bladder), and non-complicated lower UTIs are more common in women. Mild UTIs can resolve naturally, and pain killers, application of heat to the […]