C400 Biosystems

Zinc reagent

The determination of Zinc in seminal plasma, together with the reagent for Citrate and Fructose complete the Biosystems line for the diagnostic evaluation of human fertility. Zinc is used as a marker of the secretory function of the prostate gland. Low values indicate an abnormal disruption of the secretory function, possibly as a result of obstruction of the conducts due to acute or chronic inflammation. The determination of zinc in serum provides information about the metabolism of proteins and nucleic acids, and the functioning of the immune system, which is required for wound healing. A severe blood zinc deficiency is linked with depressed growth and stunting and increases the incidence of infectious diseases. Less severe zinc deficiencies are linked with immune function disorder, diarrhea, altered cognition, alopecia, vision defects and other adverse clinical conditions. Ingestion of a zinc-contaminated diet involves high blood concentrations and is associated with abdominal pain, diarrhea and nausea. Heparinized plasma samples are preferred to serum for zinc analysis to avoid possible zinc contamination from erythrocytes, platelets and leukocytes during clotting and centrifugation.
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C401 Edan

5-part differential automated hematology analyser

The newly launched DS- 600/600i 5-Part Differential Automated Hematology Analyzer adopts dual channel cell analysis system and uses only 10uL sample volume to obtain 29 parameters, 2 histograms and 2 scatter grams. Advanced semiconductor laser and flow cytometry combined with excellent chemical staining reagents make the results more accurate and reliable.
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C408 Sclavo

Platelet-derived supplement for cell culture

Entirely of human origin for in vitro cell culture applications, Lysex enables selection, expansion and differentiation of human primary cell cultures, such as adult and fetal mesenchymal stem cells (MSC), skin fibroblasts, articular chondrocytes, osteoblasts, adipose-derived cells. It enhances cell proliferation, maintaining the differentiation potential in cells otherwise difficult to expand in culture such as articular chondrocytes from elderly donors and allows culture of cells in a xeno-free environment (as it completely eliminates the need of fetal bovine serum). The fully standardized and lyophilized two-component system allows easy optimization of culture conditions for any cell type directly by the user.
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C383 SFRI image

Blood cell counter

Designed for labs that work under difficult conditions, this 3-population, 60-test/hour blood cell counter  functions in all environments and continually delivers excellent results at an affordable rate for labs. Extremely reliable, the Countender 20+ exhibits zero technical failures during the first 2 years and a mean time between failures of minimum 2 years on average. Its robustness is its greatest attribute. Featuring 20 parameters and 3 histograms, the COUNTENDER 20+ is equipped with ELENOR, an electronic noise reduction system that ensures very accurate platelet counts. An integrated data management system allows operators to easily compile coordinated reports. This blood cell counter also has one of the lowest consumption rates of reagents on the market. Coupled with simplified maintenance operations and the long shelf-life of SFRI dedicated reagents (up to 36 months), the instrument has low servicing  requirements and significantly reduces the cost of tests for labs.
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RANDOX Reagents Logo 175

Randox Homocysteine- Innovative diagnostic testing

The Randox Homocysteine assay offers laboratories a convenient two-part, liquid ready-to-use option for the accurate determination of Homocysteine concentrations in serum or plasma.  Additional benefits associated with Randox Homocysteine include two levels of calibrator included in the kit for user convenience; limited interference helping ensure accurate and reliable results are returned; and an extensive measuring range of 1.74-47.9 µmol/l facilitating comfortable detection of abnormal levels related to all Homocysteine associated disease states. Furthermore, Randox Homocysteine is suitable for use on a variety of clinical chemistry analyzers via a range of instrument specific applications.

For more information click here
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QC Logo Randox Quality Control

New ‘Supermix’ Chemistry Control

Specifically designed to replace multiple instrument specific controls the new Liquid Assayed Chemistry Premium Plus control from Randox uniquely combines 100 analytes including proteins, lipids, cardiac markers, drugs and immunoassays in a single vial to help clinical laboratories reduce valuable time and costs without compromising on performance or quality.

As a third party control laboratories are assured of a truly unbiased, independent assessment of performance.  With the added advantages associated with liquid controls and the availability of assayed target values for a range of platforms this control will enhance performance and productivity in any clinical laboratory.

  • Liquid for user convenience
  •  Assayed target values
  • Comprehensive analyte menu
  • Three clinically significant levels
  • Seven day open vial stability

For more information please click here
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C001 Sekisui cp2000

High throughput automated coagulation system

The new Coapresta 2000 (CP2000) is an automated system with a small footprint, high-throughput and a range of dedicated barcoded reagents.  The system can run up to 400 PT tests per hour. Test panels include PT, APTT, Fibrinogen, D-dimer, FDP, AT and many other new assays are in development. The system offers excellent performance, predominately ready-to-use liquid reagents,  and can be interfaced to LAS systems using point- in-space sampling, which make it an exciting new choice for laboratories seeking an efficient, high performing coagulation solution. The system is the market leading product in the higher volume system category in Japan, where it was developed. The CP2000 Coagulation System is available for purchase in Europe, Middle East and Africa through the Sekisui Diagnostics offices in Kent, UK and Rüsselsheim, Germany as of January 2014.  
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C007 GA Generic assays

Combination cell/microbead autoantibody IFT assay

The novel CytoBead technology offers for the first time the combination of autoantibody analysis by cell-based screening and the confirmation of the corresponding autoantigen reactivities by multiplexing, using the immunofluorescence technique (IFT) in one reaction environment. The CytoBead ANCA for example allows the screening of antineutrophil cytoplamsic antibodies (ANCA) on ethanol-fixed neutrophiles and the confirmation thereof using proteinase 3 (PR3) and myeloperoxidase (MPO) coated microbeads. Furthermore, the detection of Goodpasture antibodies, which can occur in 10% of rapid progressive glomerulonephritis patients, is integrated by adding glomerular basement membrane (GBM) coated microbeads. Additionally, this technology provides an ideal reaction environment for multiplexing antinuclear antibody (ANA) assessment and the detection of celiac disease specific antibodies. This assay format can be interpreted with a standard fluorescence microscope for semi-quantitative analysis and with the automated interpretation system Aklides for quantitative testing. CytoBead technology is an attractive alternative to classical, time-consuming single parameter antibody detection and is applicable for high throughput routine diagnostics.
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C404 Trinity Biotech

Troponin I point-of-care test has obtained CE marking

The ESC, ACCF, AHA and WHF stipulate that Troponin assays should demonstrate a coefficient of variation (CV) of 10% or less at the 99th percentile of the normal population, which no prior POC device could do. The high sensitivity Meritas test achieves a CV of 10% at 36pg/ml which is the 99th percentile. Results are available patient-side within 15 minutes and the Meritas analyser uses only a single drop of whole blood in a one-step process. This test will, for the first time, allow doctors to evaluate potential MI patients quickly and accurately. With CE marking achieved, Trinity Biotech now intends to release the product for sale in Europe and other carefully selected markets through its specialist cardiology distributor network.
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C006 Euroimmun

Genetic testing prevents abacavir hypersensitivity in HIV patients

The genetic risk of abacavir hypersensitivity in HIV patients can be established in whole blood samples using a new microarray based on EUROArray Direct technology. The DNA test identifies the presence of the HLAB* 57:01 allele, which is the main genetic factor associated with adverse reactions to abacavir-containing drugs. The EUROArray HLA-B*57:01 analysis is fast and simple and does not require any in-depth molecular biology knowledge. Gene sections are first amplified from the samples by multiplex polymerase chain reaction (PCR). The use of whole blood as starting material significantly reduces the costs and hands-on time required. The PCR products are then incubated with Biochip microarray slides containing immobilized complementary DNA probes. Results are evaluated and interpreted fully automatically by specialized software (EUROArrayScan). Meticulously designed primers, ready-to-use PCR components and integrated controls all contribute to the reliability of the analysis. In studies using precharacterized samples, the microarray demonstrated 100% sensitivity and 100% specificity. Abacavir is an important chemotherapeutic agent for the treatment of HIV patients. Nevertheless hypersensitivity reactions occur in 48-61% of Caucasian, 8-16% of black African and 20-22% of Hispanic carriers of the HLA-B*57:01 allele undergoing treatment, compared to 0-4% of non-carriers. Therefore, all HIV-infected patients, regardless of their ethnicity, should be tested for the presence of the HLA-B*57:01 allele before starting treatment with drugs containing abacavir sulphate (e.g. Ziagen tablets and suspension, Kivexa tablets and Trizavir tablets).
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