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The science of safety | Promoting ergonomic practices in the lab

By LaNiesha Littleton Repetitive manual tasks are common in many laboratories, making the risk of repetitive strain injuries and musculoskeletal disorders a significant concern for businesses and employees alike. This article highlights the importance of injury prevention through expert support and ergonomic solutions, and explores how the workplace health and safety landscape is now being […]

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Insight into DNA methylation analysis

The association of epigenetic changes with disease pathogenesis is the subject of much study. CLI caught up with Dr Kathleen Barnes (Oxford Nanopore Technologies) to find out more about how DNA methylation is linked to disease as well as developments in methods of DNA methylation analysis for improving disease diagnosis, prognostic stratification and therapy.

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Using ferritin as a biomarker for hemophagocytic lymphohistiocytosis can reduce delays in treatment due to negative or pending hemophagocytosis results

Using ferritin as a biomarker for hemophagocytic lymphohistiocytosis can reduce delays in treatment due to negative or pending hemophagocytosis results

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Molecular diagnosis of the myeloproliferative neoplasms

By Dr Stephen Langabeer The myeloproliferative neoplasms of polycythemia vera, essential thrombocythemia and primary myelofibrosis are clonal hematopoietic disorders characterized by an over-production of mature blood cells. Molecular evaluation is a key component of differentiating malignancy from a host of reactive causes with mutations in JAK2, CALR and MPL genes present in the majority of […]

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Revolutionary ‘Bridge RNA’ system unlocks precision genome editing capabilities

Researchers at the Arc Institute have unveiled a groundbreaking genetic engineering tool called the bridge recombinase mechanism, offering unprecedented precision in DNA recombination and rearrangement. The study, published in Nature [1], details the discovery of the first DNA recombinase that utilises a non-coding RNA for sequence-specific selection of target and donor DNA molecules.

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Human induced pluripotent stem cells: A game-changer for drug testing

Researchers at the Fraunhofer Institute for Biomedical Engineering IBMT have developed innovative solutions for the production and preservation of human induced pluripotent stem (hiPS) cells, potentially revolutionising drug discovery and toxicity testing processes.

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Syntegon’s Pharmatec unveils modular bioprocessing platform

Syntegon subsidiary Pharmatec recently launched its new Modular Bioprocessing Platform (MBP), designed to address key challenges in biopharmaceutical production. The highly flexible, fully integrated and automated solution was developed for biologic drug substances, with configurations available for a range of microbial and mammalian cell culture applications.

Torrey Pines EchoTherm

Precision temperature control for laboratory samples

Torrey Pines Scientific has introduced a new chilling and heating dry bath designed for precise temperature control in clinical laboratory settings. The EchoTherm™ Model IC50 offers a range of features tailored to the needs of molecular biology and other laboratory applications.

Sakura Finetek Tissue Tek xPrint LP Laser Printer

New laser cassette printer advances tissue sample identification in pathology labs

Sakura Finetek Europe has unveiled its latest innovation in tissue sample identification technology, the Tissue-Tek xPrint LP Laser Cassette Printer. This device promises to elevate laboratory workflows and enhance digital integration in pathology laboratories.

Bio Rad ddSEQ Single Cell 3 RNA Seq Kit

Bio-Rad launches new single-cell RNA-Seq Kit and analysis software

Bio-Rad Laboratories, Inc. has introduced a new kit and software package for single-cell transcriptome and gene expression research. The ddSEQ™ Single-Cell 3’ RNA-Seq Kit, designed for use with Bio-Rad’s ddSEQ Cell Isolator, aims to provide high-quality single-cell 3’ RNA-Seq libraries efficiently and cost-effectively.