Vetter

Vetter expands global manufacturing capacity for injectable therapeutics

Leading contract development and manufacturing organisation (CDMO) Vetter has announced significant expansion plans in both the United States and Germany, aiming to meet the growing demand for outsourced development and manufacturing of injectable medications.

Scherm­afbeelding 2024 07 01 om 16.52.50

ELRIG UK announces keynote speakers for Drug Discovery 2024

The European Laboratory Research & Innovation Group (ELRIG) UK has revealed the keynote speakers for its flagship conference, Drug Discovery 2024. The event, scheduled for 2-3 October at ExCeL London, will feature presentations from two distinguished scientists in the field of pharmaceutical research and development.

AdobeStock 706467109

The science of safety | Promoting ergonomic practices in the lab

By LaNiesha Littleton Repetitive manual tasks are common in many laboratories, making the risk of repetitive strain injuries and musculoskeletal disorders a significant concern for businesses and employees alike. This article highlights the importance of injury prevention through expert support and ergonomic solutions, and explores how the workplace health and safety landscape is now being […]

AdobeStock 585907876

Insight into DNA methylation analysis

The association of epigenetic changes with disease pathogenesis is the subject of much study. CLI caught up with Dr Kathleen Barnes (Oxford Nanopore Technologies) to find out more about how DNA methylation is linked to disease as well as developments in methods of DNA methylation analysis for improving disease diagnosis, prognostic stratification and therapy.

AdobeStock 802968907

Using ferritin as a biomarker for hemophagocytic lymphohistiocytosis can reduce delays in treatment due to negative or pending hemophagocytosis results

Using ferritin as a biomarker for hemophagocytic lymphohistiocytosis can reduce delays in treatment due to negative or pending hemophagocytosis results

Scherm­afbeelding 2024 07 01 om 15.51.59

Molecular diagnosis of the myeloproliferative neoplasms

By Dr Stephen Langabeer The myeloproliferative neoplasms of polycythemia vera, essential thrombocythemia and primary myelofibrosis are clonal hematopoietic disorders characterized by an over-production of mature blood cells. Molecular evaluation is a key component of differentiating malignancy from a host of reactive causes with mutations in JAK2, CALR and MPL genes present in the majority of […]

BridgeRNA 2

Revolutionary ‘Bridge RNA’ system unlocks precision genome editing capabilities

Researchers at the Arc Institute have unveiled a groundbreaking genetic engineering tool called the bridge recombinase mechanism, offering unprecedented precision in DNA recombination and rearrangement. The study, published in Nature [1], details the discovery of the first DNA recombinase that utilises a non-coding RNA for sequence-specific selection of target and donor DNA molecules.

hips bioreactor

Human induced pluripotent stem cells: A game-changer for drug testing

Researchers at the Fraunhofer Institute for Biomedical Engineering IBMT have developed innovative solutions for the production and preservation of human induced pluripotent stem (hiPS) cells, potentially revolutionising drug discovery and toxicity testing processes.

syntegon2

Syntegon’s Pharmatec unveils modular bioprocessing platform

Syntegon subsidiary Pharmatec recently launched its new Modular Bioprocessing Platform (MBP), designed to address key challenges in biopharmaceutical production. The highly flexible, fully integrated and automated solution was developed for biologic drug substances, with configurations available for a range of microbial and mammalian cell culture applications.

Torrey Pines EchoTherm

Precision temperature control for laboratory samples

Torrey Pines Scientific has introduced a new chilling and heating dry bath designed for precise temperature control in clinical laboratory settings. The EchoTherm™ Model IC50 offers a range of features tailored to the needs of molecular biology and other laboratory applications.