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Using ferritin as a biomarker for hemophagocytic lymphohistiocytosis can reduce delays in treatment due to negative or pending hemophagocytosis results

Using ferritin as a biomarker for hemophagocytic lymphohistiocytosis can reduce delays in treatment due to negative or pending hemophagocytosis results

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Molecular diagnosis of the myeloproliferative neoplasms

By Dr Stephen Langabeer The myeloproliferative neoplasms of polycythemia vera, essential thrombocythemia and primary myelofibrosis are clonal hematopoietic disorders characterized by an over-production of mature blood cells. Molecular evaluation is a key component of differentiating malignancy from a host of reactive causes with mutations in JAK2, CALR and MPL genes present in the majority of […]

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Revolutionary ‘Bridge RNA’ system unlocks precision genome editing capabilities

Researchers at the Arc Institute have unveiled a groundbreaking genetic engineering tool called the bridge recombinase mechanism, offering unprecedented precision in DNA recombination and rearrangement. The study, published in Nature [1], details the discovery of the first DNA recombinase that utilises a non-coding RNA for sequence-specific selection of target and donor DNA molecules.

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Human induced pluripotent stem cells: A game-changer for drug testing

Researchers at the Fraunhofer Institute for Biomedical Engineering IBMT have developed innovative solutions for the production and preservation of human induced pluripotent stem (hiPS) cells, potentially revolutionising drug discovery and toxicity testing processes.

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Syntegon’s Pharmatec unveils modular bioprocessing platform

Syntegon subsidiary Pharmatec recently launched its new Modular Bioprocessing Platform (MBP), designed to address key challenges in biopharmaceutical production. The highly flexible, fully integrated and automated solution was developed for biologic drug substances, with configurations available for a range of microbial and mammalian cell culture applications.

Torrey Pines EchoTherm

Precision temperature control for laboratory samples

Torrey Pines Scientific has introduced a new chilling and heating dry bath designed for precise temperature control in clinical laboratory settings. The EchoTherm™ Model IC50 offers a range of features tailored to the needs of molecular biology and other laboratory applications.

Sakura Finetek Tissue Tek xPrint LP Laser Printer

New laser cassette printer advances tissue sample identification in pathology labs

Sakura Finetek Europe has unveiled its latest innovation in tissue sample identification technology, the Tissue-Tek xPrint LP Laser Cassette Printer. This device promises to elevate laboratory workflows and enhance digital integration in pathology laboratories.

Bio Rad ddSEQ Single Cell 3 RNA Seq Kit

Bio-Rad launches new single-cell RNA-Seq Kit and analysis software

Bio-Rad Laboratories, Inc. has introduced a new kit and software package for single-cell transcriptome and gene expression research. The ddSEQ™ Single-Cell 3’ RNA-Seq Kit, designed for use with Bio-Rad’s ddSEQ Cell Isolator, aims to provide high-quality single-cell 3’ RNA-Seq libraries efficiently and cost-effectively.

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Novel liquid biopsy could detect and monitor aggressive small cell lung cancer

A new lab assay developed by researchers at Fred Hutch Cancer Center in Seattle could make diagnosis and treatment of small-cell lung cancer and non-small cell lung cancer easier.

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SyntheMol AI generates 25,000 novel antibiotics and their recipes in 9 hours

Generative AI develops 6 new drugs that can kill resistant strains of A. baumannii With nearly 5 million deaths linked to antibiotic resistance globally every year, new ways to combat resistant bacterial strains are urgently needed.