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The virulent pathogen that causes the disease tularemia, or “rabbit fever,” was weaponised during past world wars and is considered a potential bioweapon. Through a new study of the coccobacillus Francisella, Los Alamos National Laboratory researchers are working to use DNA markers to discern related but relatively harmless species as they are identified and to […]
A gene involved in brain development that can lead to severe disability and infant death has been identified by scientists. Mutations in the gene cause profound developmental problems and seizures in young children, researchers have found. Scientists and doctors worked with children with a range of severe problems, including seizures and abnormal brain scans, and […]
Following a three-year study of the Arizona State University football program, researchers at the Translational Genomics Research Institute (TGen) have created the largest dataset to date of extracellular small RNAs, which are potential biomarkers for diagnosing medical conditions, including concussions. The study amassed a collection of biomarkers from the ASU student-athletes’ biofluids: blood, urine […]
Why do some breast cancers respond to treatment while others resist it? A study led by researchers at the University of North Carolina Lineberger Comprehensive Cancer Center may provide insight into this important question. The researchers report at the San Antonio Breast Cancer Symposium they have identified biomarkers they believe can be used as part […]
As more biomarker-based studies open, such testing will increase opportunities to match patients with clinical trials. Nearly three-quarters of patients with advanced cancer could be referred to a potential targeted treatment based on the results of a comprehensive analysis of their tumour’s genetic landscape, a new analysis finds. The study suggests the value of so-called […]
Five simple medical tests together provide a broader and more accurate assessment of heart-disease risk than currently used methods, cardiologists at UT Southwestern Medical Center found. Combined, results from the five tests – an EKG, a limited CT scan, and three blood tests – better predict who will develop heart disease compared with standard strategies […]
Most of us would be lost without Google maps or similar route-guidance technologies. And when those mapping tools include additional data about traffic or weather, we can navigate even more effectively. For scientists who navigate the mammalian genome to better understand genetic causes of disease, combining various types of data sets makes finding their way […]
Scientists have discovered the genetic mutation that causes the rare skin disease, keratolytic winter erythema (KWE), or ‘Oudtshoorn skin’, in Afrikaners. KWE causes a redness of the palms and soles with consecutive cycles of peeling of large sections of thick skin, often exacerbated during winter months. Oudtshoorn is a town in the Western Cape province […]
Chemistry researchers develop a simple diagnostic test that can identify the level of cocaine in a person’s urine or oral fluid. The new test offers a low cost, quick method that could be used for testing at the roadside, in the workplace or in prisons Current commercially available portable testing kits can give false positive […]
What can’t graphene do? You can scratch “detect cancer” off of that list. By interfacing brain cells onto graphene, researchers at the University of Illinois at Chicago have shown they can differentiate a single hyperactive cancerous cell from a normal cell, pointing the way to developing a simple, non-invasive tool for early cancer diagnosis. “This […]
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