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New developments in LC-MS/MS

In their aim to support researchers and clinicians, companies such as Thermo Fisher Scientific are also at the forefront of their own R&D. CLI caught up with Dr Edward Goucher, Senior Manager of Business Development, to discuss their new developments.

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Analysis of illicit drugs in purchased and seized electronic cigarette liquids from the United Kingdom 2014-2021

Frinculescu A, Coombes G, Shine T et al. Drug Test Anal 2022;doi:10.1002/dta.3277 Increasing popularity and known shortfalls in the regulation of electronic cigarettes (ECs) emphasizes the urgent need for closer content monitoring and for comprehensible information on their possible health effects.

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Diagnostic value of combined detection of tumour markers for 143 cases of primary hepatic carcinoma

by Xijun Min, Dr Yan Li, Liuyan Chen, Chengwei Yao, Dr Xi Qin As a traditional tumour marker for the diagnosis of early primary hepatic carcinoma (PHC), alpha fetoprotein (AFP) has a low positive rate. Serum glypican 3 (GPC3) is a novel biomarker, and the combined examination of GPC3 and AFP will provide a new […]

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The Intelligent Analyzer

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Urinary ALCAM as a biomarker for lupus nephritis

by Dr Cherie Ng and Dr Chaim Putterman Lupus nephritis is an immune-mediated glomerulonephritis that causes significant morbidity and mortality in patients with systemic lupus erythematous, a multisystem autoimmune disease. Non-invasive biomarkers are necessary to track disease and treatment response. Urinary ALCAM is a potential biomarker that samples the kidney and is relevant to the […]

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For your emergency markers

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Secretoneurin: a potential complementary cardiovascular biomarker

Secretoneurin is a novel prognostic biomarker that may predict mortality in heart failure and the occurrence of ventricular arrhythmias. CLI caught up with Professor Torbjørn Omland (University of Oslo, Oslo, Norway) to find out more about it.

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A simple tool for a crazy task NORMALIZATION

In a snap with the ASSIST PLUS Pipetting Robot and D-ONE Single Channel Module

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Paper spray ionization mass spectrometry method detects Parkinson’s disease biomarkers in less than three minutes

Those of you who regularly cast an eye over the Editor’s Letter in CLI will know that we have been closely following the story of the development of a sebum-based biomarker test to diagnose Parkinson’s disease (PD; Editor’s letters in the Feb/March issues of CLI in 2018 and 2021).