Further extending the range of infectious disease diagnostic assays for use on the DiaSorin Liaison Iam analyser, the Iam HSV molecular assay provides rapid and reliable differential detection of herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) in human cerebrospinal fluid (CSF), vesicle swabs, plasma and whole blood, making it of enormous value in the diagnosis of herpes simplex encephalitis and potentially severe HSV infections in transplant patients and other immunocompromised individuals.  Together with Iam VZV for the detection of clinically relevant subtypes of Varicella Zoster Virus (VZV), these assays provide valuable information for the timely treatment of severe alpha-herpesvirus infections. HSV-1 is an important cause of fatal sporadic encephalitis, although HSV-2 is more commonly associated with herpes simplex encephalitis in neonates and immunosuppressed individuals.  Early diagnosis and treatment are important to reduce and prevent neurological damage.  In transplant patients and other immunocompromised hosts, HSV may cause severe infections, frequently disseminating to the visceral organs, and can be life or organ threatening. Nucleic acid tests are the method of choice for the diagnosis and characterization of HSV infection, following baseline serology, offering greater sensitivity than viral culture.  Furthermore, molecular detection of HSV DNA in CSF is recommended for the diagnosis of herpes simplex encephalitis.  The ability to differentiate between HSV types can provide important prognostic information, particularly in the diagnosis of genital herpes. Like HSV, VZV is the cause of significant morbidity and mortality in transplant patients and other immunocompromised individuals.  Immunocompromised children, particularly those with leukemia, are reported to be at risk of visceral complications and even death folllowing VZV infection. Complications occur in about 20% of VZV infected immunocompromised patients and include interstitial or necrotizing pneumonia, viral hepatitis with acute liver failure, coagulopathies and bacterial superinfections. Offering excellent diagnostic sensitivity (>95% for Iam VZV and >98.5% for Iam HSV) and specificity (100% for Iam VZV and 100% for Iam HSV), and with faster time to results than conventional real-time PCR, the assays provide rapid and accurate molecular confirmation of alpha-herpesvirus infections.  Furthermore, the small footprint, ease of use and scalable design of the benchtop Liaison Iam molecular instrument makes it ideal for use in laboratory facilities of all sizes, including those that are located close to the patient.  

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The Endura MD mass spectrometer LC-MS for in vitro diagnostic use delivers excellent sensitivity for a wide range of compounds and matrices and minimizes signal noise by removing more solvent vapour and blocking neutrals. The instrument provides five orders of dynamic range for accurate quantitation of even low-concentration or limited samples and features ultrafast selected-reaction monitoring (SRM) so more transitions can be monitored for greater confidence. It accommodates both HESI and APCI probes, which can be operated in either positive or negative ion modes to meet varied analytical demands.

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CS-6400 Auto-Chemistry System, utilizing advanced technology, offers an extremely efficient workflow to achieve the laboratory’s turnaround time goals. The cost-effective modular combination design and optional ISE module provide customers with flexible and multiple choices. The throughput of each photometric module is 1600 tests/hour and that of each ISE unit is 480 tests/hours. The highest throughput can reach 7360 tests/hour with 4 photometric modules and two ISE module units.

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Axis-Shield is excited to announce the launch of our new assay for the measurement of Glycated Haemoglobin (HbA1c) in human whole blood.
Regular monitoring of HbA1c levels is a key component of diabetic blood glucose control and the Axis-Shield assay provides a convenient method for use in routine testing laboratories. The Latex Turbidimetric Immunoassay methodology gives a highly accurate and precise method combined with a number of convenient features for the user and the lab. Operator handling time is reduced as the assay uses only 2 liquid-stable reagents so there is no requirement for pre-analytical mixing of reagents. Reagents are supplied in instrument-specific packaging so they can be directly loaded onto many systems without the need to further decant. The use of only two reagents also means that only one instrument channel is required, freeing space on your instrument.

The Axis-Shield assay removes the need for a simultaneous Total Hb measurement by utilising a monoclonal antibody against HbA1c.
The reagents can be used on any clinical chemistry instrument and programming is simple – applications for many common instruments are available from Axis-Shield. A 2-level control pack and 5-level calibrator pack are also available.
The Axis-Shield assay is certified by the National Glycohemoglobin Standardisation Program (NGSP).
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This fully automated electrolyte analyser is available in two versions: model EX-D with autosampler and EX-Ds without autosampler. It is equipped with an ion selective electrode for measuring sodium, potassium, and chloride in whole blood, serum and diluted urine. Twenty samples can be processed in one run and results are available within 36 seconds/test. An auto-retest function allows for the automatic retesting of samples with abnormal values. Emergency samples can be tested at any time during routine measurement. Electrodes are highly sensitive and C.V is less than 0.5%. A radiofrequency identification (RFID) reader attached to the analyser and IC (integrated circuit) tags attached to reagents provides reagent identification. The IC tag records the expiry date and the concentration of the reagent at the time of shipment.
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