Siemens Healthineers’s INNOVANCE assays help improve efficiencies, workflow and resource management following a COVID-19 diagnosis.
In hospitalised COVID-19 patients, elevated D-dimer levels have been found to be strongly associated with disease severity and even mortality reflecting the procoagulant status and high thrombotic risk observed in many COVID-19 patients. Therefore, the monitoring of D-dimer levels is recommended for hospitalised COVID-19 patients to stratify their thrombotic risk including testing for deep vein thrombosis and pulmonary embolism and guiding treatment over the course of the disease.
Treating COVID-19 patients with anticoagulants has been associated with improved outcomes, both in and out of the intensive care unit setting.
Accurate antithrombin measurement in COVID-19 patients undergoing anticoagulant treatment may be useful to determine the efficacy of anticoagulant therapy as antithrombin levels might be reduced.
Siemens Healthineers has a comprehensive portfolio of assays for detection and monitoring of coagulation disorders.
For more information, visit: https://www.siemenshealthineers.com/hemostasis/ innovance-reagents-for-coagulation-disorders Read more
https://clinlabint.com/wp-content/uploads/sites/2/2020/08/PRODUCT_SIEMENS_1.jpg2136953wmediahttps://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png3wmedia2020-08-26 09:16:522021-01-08 11:20:33INNOVANCE reagents support management of COVID-19 patients
Germany-based Tosoh Bioscience has introduced SkillPak 1 mL and 5 mL pre-packed process development columns designed for fast method development and resin screening of monoclonal antibodies, antibody constructs, oligonucleotides, proteins, and viruses.
Tosoh Bioscience, a subsidiary of Tosoh Corporation in Japan, specialises in providing chromatographic solutions for the separation and purification of biomolecules.
Pre-packed with TOYOPEARL®, TSKgel® or Ca++Pure-HA® process chromatography media, SkillPak 1 mL and 5 mL columns deliver high performance and offer scalability and convenience. These columns are ready to use upon receipt and show excellent physical strength and ideal flow characteristics for industrial downstream processing. The pre-packed columns are available with short delivery times in affinity, anion and cation exchange, hydrophobic interaction and size exclusion chromatographic modes. Optimal performance is guaranteed with the columns and they can be operated directly with commonly used low or medium pressure liquid chromatography systems.
SkillPak 1 mL and 5 mL pre-packed columns are available for sale in Europe, Africa and the Middle East.
For more information, visit: https://www.separations. eu.tosohbioscience.com/solutions/process-mediaproducts/ process-development/skillpak Read more
Awareness Technology’s new ChemWell 2 analyzer for ELISA and chemiluminescent (CLIA) is now available.
The ChemWell 2 is a two-probe, two-plate automatic combo analyzer. For 20 years the company has produced single-plate ChemWell automatic ELISA and CLIA systems with the flexibility to run both modes simultaneously even within the same plate. With laboratories expanding serology requirements, the two-plate system is expected to be a more suitable primary instrument for lower throughput labs, and ideal for off-line assays in higher throughput settings.
ChemWell’s flexibility in both hardware and software is key to automating a wide variety of unrelated test methods. Separate probes are used for samples and reagents with an option for disposable tips. Filters range from 405 nm – 630 nm; dispense volume from 2μL to 1.95 ml; plate washing routines, temperature control, and mixing are programmable. Intuitive software offers on-board predilutions, multiple calibration options, replicates, statistics, QC tracking, barcoded sample ID and data management. Additionally, it schedules assays to prevent timing conflicts while providing optimal throughput. An optional laptop stand conserves bench space.
For more information, visit: www.awaretech.com Read more
https://clinlabint.com/wp-content/uploads/sites/2/2020/08/PRODUCT_AWARENESS_TECHNOLOGY.jpg4617293wmediahttps://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png3wmedia2020-08-26 09:16:522021-01-08 11:20:33Awareness Technology releases ChemWell 2, a two-plate ELISA and chemiluminescent analyzer
Siemens Healthineers has a released an informative eBook titled “Coagulation abnormalities in COVID-19 patients – current testing and treatment protocols” to provide quick access to coagulation testing and treatment recommendations.
The eBook can be downloaded for free from their website: https://bit.ly/2CcpB5I
Because coagulation tests are important in the management of COVID-19 patients, the company has compiled an eBook for quick access to:
Thrombosis risk factors
An ISTH-recommended coagulation testing algorithm
Leading recommendations for anticoagulation treatment
Relevant parameters for patient monitoring
The eBook provides an overview of COVID-19 and thrombosis; it looks at laboratory testing in the identification of coagulation abnormalities in COVID-19 patients; and provides information on the treatment of coagulation abnormalities in COVID-19 patients.
Authors of the eBook write that while it’s not unusual for infections to raise the risk of clotting, the COVID-19 virus is associated with an unprecedented range of clotting-related disorders in affected patients. “From benign skin lesions on the feet to life-threatening thrombotic events, the COVID-19 virus has demonstrated a strikingly high prevalence of deadly blood clots. Studies show that about 25% and even up to 70% of critically ill patients have confirmed venous thromboembolism or pulmonary embolism. Another study found that approximately 70% of COVID-19 patients who died had disseminated intravascular coagulation.”
They add that Siemens Healthineers’s coagulation tests play an important role in the diagnosis, treatment, and management of coagulation abnormalities in COVID-19 patients and point out that the company has changed their production model to produce these assays at a higher volume than ever before.
“We are proud to support you in the fight against COVID-19. Behind every healthcare professional there are 53,000 Healthineers,” Siemens Healthineers says. Read more
https://clinlabint.com/wp-content/uploads/sites/2/2020/08/PRODUCT_SIEMENS_2.jpg4176923wmediahttps://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png3wmedia2020-08-26 09:16:522021-01-08 11:20:32Siemens Healthineers releases free eBook on coagulation testing protocols for COVID-19 patients
Thermo Fisher Scientific has introduced several new products that build on its leading Orbitrap platform and expand research applications. The new Thermo Scientific Orbitrap Exploris 240 mass spectrometer is designed to give scientists working in proteomics, metabolomics, biopharmaceutical characterisation and small-molecules, the analytical performance required for research and high-throughput analyses. The company says the new system will advance discovery and identification with increased accuracy for confident scale-up, while providing operational simplicity and streamlining time-to-result.
Thermo Fisher Scientific pointed out that the new mass spectrometer delivers qualitative and quantitative capabilities synonymous with Orbitrap high-resolution accurate-mass (HRAM) spectrometry, with internal calibration that assures consistent data quality and decision making. These newest systems extend the Thermo Scientific Orbitrap Exploris portfolio of HRAM systems, which were introduced in 2019 with the release of the new-generation Thermo Scientific Orbitrap Exploris 480 mass spectrometer. Software Thermo Scientific Proteome Discoverer 2.5 software provides high confidence during peptide identification, accurate quantification and high throughput data analysis for proteomics researchers. Deep learning-based prediction of tandem mass spectra, facilitated through a new collaboration with MSAID, a software company transforming proteomics through deep learning, enables more scientists to benefit from major improvements in identification confidence and reproducibility.
To further enhance characterisation of protein biotherapeutics and oligonucleotide therapeutics, biopharmaceutical laboratories use the Thermo Scientific BioPharma Finder 4.0 software, which provides greater flexibility and customisation for this growing industry.
For small molecule researchers, Thermo Scientific Compound Discoverer 3.2 software further automates unknown compound identification performed on Thermo Scientific Orbitrap Gas Chromatography- Mass Spectrometry (GC-MS) systems to improve productivity.
In addition, the new Thermo Scientific Xcalibur 4.4 software brings the AcquireX intelligent data acquisition workflow to Thermo Scientific Orbitrap Exploris mass spectrometry platform users, enabling the fully automated acquisition of high quality MS/MS data and reducing manual input and repeat runs. Collaboration Thermo Fisher Scientific’s collaboration with Evosep, a leading provider of sample preparation technologies for protein-based clinical research, supports the development of high-throughput clinical research workflows for profiling large plasma sample cohorts for proteomics, translational research and pharmaceutical applications. This partnership recently led to the launch of an automated ultra-high throughput plasma protein profiling platform, combing the power of the new Thermo Scientific Orbitrap Exploris 240 mass spectrometer with the Evosep One liquid chromatography solution.
The company’s collaboration with Biognosys, a leading developer of next-generation proteomics solutions, resulted in the development of data-independent acquisition mass spectrometrybased workflows, which enhances sensitivity and coverage for proteomic research in translational and clinical labs. The collaboration includes a novel FAIMS-DIA method that features the Thermo Scientific FAIMS Pro interface, which improves selectivity, reproducibility and proteome coverage, as well as new methods that streamline discovery by combining Thermo Scientific SureQuant Targeted Assay Kits and the Biognosys PQ500 kit in a single workflow.
For more information, visit: www.thermofisher.com Read more
https://clinlabint.com/wp-content/uploads/sites/2/2020/08/AD_THERMO_FISHER.jpg5325013wmediahttps://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png3wmedia2020-08-26 09:16:522021-01-08 11:20:32Thermo Fisher Scientific introduces new mass spectrometry systems
Shimadzu, a leader in analytical instrumentation, has introduced the new HIC-ESP (Ion Chromatograph) featuring a built-in electrodialytic suppressor. This anion suppressor minimizes band spreading and achieves high sensitivity and reliable performance for the quantitative determination of anions.
The suppressor is rugged, providing stable functionality over long periods of operation. The system’s small footprint requires minimal bench space. HIC-ESP covers a wide range of applications in environmental testing, pharma, chemistry and food science.
The HIC-ESP modular inert flow path system integrates a system controller, degasser, pump, CDD detector with temperature-controlled flow cell, autosampler, slim-line oven and the anion suppressor. The system combines a number of special features providing reliable analytical results: Excellent solvent delivery performance, low carryover, fast injection speed (as low as 10 sec), high sample injection precision and repeatability, precise oven temperature regulation and more.
In addition, the ion chromatography system integrates seamlessly with Shimadzu’s LabSolutions platform. This allows users to easily manage parameter setting for IC analysis, batch analyses, autoshutdown, data processing and report creation. Data integrity is assured with the addition of LabSolutions DB and LabSolutions CS.
For more information, visit: www.shimadzu.eu/ liquid-chromatography/nexera/hicesp Read more
https://clinlabint.com/wp-content/uploads/sites/2/2020/08/AD_SHIMADZU_01.jpg5032823wmediahttps://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png3wmedia2020-08-26 09:16:522021-01-08 11:20:32Shimadzu introduces new HIC-ESP ion chromatograph
Oxford Immunotec Global has released the T-SPOT Discovery SARS-CoV-2 test kit. The kit is for research use only and could make a significant contribution towards development of a new tool to manage the COVID-19 pandemic.
T-SPOT Discovery SARS-CoV-2 builds on Oxford Immunotec’s experience with TB diagnosis and the assessment of immune response to CMV in transplant patients, to apply the Company’s established, proprietary T-SPOT technology to the fight against COVID-19.
While serology is able to detect antibodies to SARS-CoV-2 in the blood of some individuals after infection, little is known about how this confers immunity to COVID-19. T-SPOT technology goes further than simple serology by interrogating the immune system’s T cell response and will enable research into the measurement of the strength of that response to SARS-CoV-2. The strength of this response may be linked to protection from reinfection.
Commenting on the technology, Phill Keefe, Senior Vice President Product Design, Development and Delivery at Oxford Immunotec, said: “Not everyone with COVID-19 infection has detectable antibodies in serology tests, and this may be a bigger problem in the majority who experience only mild or no symptoms. Also, it is not yet clear whether the presence of anti-bodies confers immunity. T cell responses develop before antibody generation and can independently provide protection, so studying T cells could give us new insights into immunity to COVID-19.”
T-SPOT technology is approved in over 60 countries for clinical use to detect TB infection. With over 20 million clinical tests since release, T-SPOT technology:
Uses a standardized sample prepared from peripheral blood which: – Reduces the influence of factors which might affect results, such as other treatments – Standardises cell numbers in the test to normalise for cell number variations between samples
Allows the number of responding T cells to be enumerated for a more precise assessment of the T cell response
Is able to maintain performance, even in samples from immunosuppressed individuals
Can be run in high-volume labs enabling large testing programs to be rolled out.
T-SPOT technology can also be automated using the T-Cell Select reagent kit. Automation solutions are available for low, medium and high throughput settings.
For more information, visit: go.oxfordimmunotec. com/t-spot_discovery_SARS_CoV-2 Read more
https://clinlabint.com/wp-content/uploads/sites/2/2020/08/PRODUCT_IMMUNOTEC.jpg3266983wmediahttps://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png3wmedia2020-08-26 09:16:522021-01-08 11:20:31Oxford Immunotec releases T-SPOT Discovery SARS-CoV-2 kit for research into measuring T cell immune response to SARS-CoV-2
Ansh labs has launched two new immunoassays, SARS-CoV2 IgG and IgM ELISAs, to assist in the fight against the Covid-19 pandemic.
Ansh Labs is releasing these two kits for sale in the United States under the provisions outlined in Section D of Policy for Diagnostic Tests for Coronavirus Disease-2019 during the Public Health Emergency. At the time of going to press, these tests were under review by the FDA for an Emergency Use Authorization.
IgM antibody is the first to be produced in response to viral proteins (antigens) and will be primarily detectable during the early onset of the disease. IgG antibodies are long-lasting and can persist in the bloodstream for many years after infection. This test has the advantage of detecting not only individuals with active infection (IgM), but also those who were previously exposed to the virus and may have subsequently developed immunity (IgG).
Testing for SARS-CoV2 antibodies can help in epidemiological surveillance about the spread of the virus and possible herd immunity. Ansh Labs’ SARS-CoV2 ELISAs are highly accurate with IgG ELISA offering 96% specificity and IgM ELISA offering 99% specificity.
For more information, visit: www.covid-diagnostics.com Read more
https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png003wmediahttps://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png3wmedia2020-08-26 09:16:522021-01-08 11:20:31Ansh labs launches two new immunoassays for SARS-COV2
Logan, UT, January 17, 2020 – ELITechGroup Inc., recognized worldwide as slide staining and cytocentrifuge technologic pioneers and innovators, with nearly 30 patents, over the 35-year lifespan of Aerospray staining technology, announces the launch of the Aerospray Cytology Slide Stainer Cytocentrifuge. The ELITechGroup’s Aerospray Cytology Slide Stainer/Cytocentrifuge automates the preparation and staining of liquid based cytology specimens to facilitate the examination of an array of cell differentiations utilizing Papanicolaou staining techniques. The advantages of the Aerospray Cytology Slide Stainer/Cytocentrifuge is that the device performs two functions of sample preparation through cytocentrifugation and sample staining. The system maximizes cell recovery to the slide through the use of its Cytopro® Rotor, eliminates cross-contamination with an application of fresh stain for each slide, and provides programmable regressive and progressive staining capabilities that can be stored in memory to meet the needs and preferences of any end user. The instrument standardizes staining across multiple labs, provides consistently high-quality control, is low maintenance, reduces the labor/cost per slide, enables laboratory compliance, and is the perfect back-up for high automation laboratories for specialty staining and during maintenance. “ELITechGroup’s portfolio of Aerospray slide stainers and cytocentrifuges has enabled the company to develop a worldwide reputation for performance and reliability. Our new Aerospray Cytology Stainer/Cytocentrifuge proves our commitment to ongoing innovation by expanding into new laboratories where we can offer superior staining results,” says Bryce McEuen, Vice President, Biomedical Systems. ELITechGroup will be showcasing the Aerospray Cytology Slide Stainer/Cytocentrifuge at key industry events throughout the year of 2020. Learn more at AerosprayStaining.com. About ELITechGroup
ELITechGroup is a privately held group of worldwide manufacturers and distributors of in vitro diagnostic equipment and reagents for clinical systems, microbiology, molecular diagnostics, hematology, cytology, and sweat test systems. Their mission is to improve patient care by empowering laboratories to do more in less time, with accuracy, to enable rapid and accurate course of treatment for patients. Read more
NovaTec provides reliable direct pathogen and antibody detection assays to aid in the diagnosis of SARS-CoV-2. These tests are CE-IVD marked. The development of the assays has been spearheaded by affiliate companies Gold Standard Diagnostics, NovaTec Immundiagnostica, and VIROTECH Diagnostics.
The NovaLisa SARS-CoV-2 (COVID-19) ELISA serological assays feature separate detection of IgG, IgA, and IgM antibodies. These three assays use the nucleocapsid protein (N protein) as antigen for the detection of antibodies to SARS-CoV-2, as it plays an important role in viral pathogenesis, replication and RNA packaging. NovaLisa assays can be automated on several open ELISA systems to provide quick results.
The GSD NovaPrime SARS-CoV-2 is a onestep reverse transcription multiplex Real-Time PCR for the direct detection of SARS-CoV-2. The assay simultaneously detects two target sequences inside the N gene. The multiplex PCR enables a streamlined workflow in one reaction and provides results in approximately 2 hours. An extraction/inhibition control and a positive control are included in the kits. The PCR assay demonstrates excellent performance and no cross-reactivity with common human coronavirus strains. Read more
https://clinlabint.com/wp-content/uploads/sites/2/2020/08/PRODUCT_NOVATEC.jpg5007683wmediahttps://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png3wmedia2020-08-26 09:16:522021-01-08 11:20:31NovaTec Immundiagnostica’s assays aid diagnosis of SARS-COV-2
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INNOVANCE reagents support management of COVID-19 patients
, /in Corona News, Product News /by 3wmediaSiemens Healthineers’s INNOVANCE assays help improve efficiencies, workflow and resource management following a COVID-19 diagnosis.
In hospitalised COVID-19 patients, elevated D-dimer levels have been found to be strongly associated with disease severity and even mortality reflecting the procoagulant status and high thrombotic risk observed in many COVID-19 patients. Therefore, the monitoring of D-dimer levels is recommended for hospitalised COVID-19 patients to stratify their thrombotic risk including testing for deep vein thrombosis and pulmonary embolism and guiding treatment over the course of the disease.
Treating COVID-19 patients with anticoagulants has been associated with improved outcomes, both in and out of the intensive care unit setting.
Accurate antithrombin measurement in COVID-19 patients undergoing anticoagulant treatment may be useful to determine the efficacy of anticoagulant therapy as antithrombin levels might be reduced.
Siemens Healthineers has a comprehensive portfolio of assays for detection and monitoring of coagulation disorders.
For more information, visit: https://www.siemenshealthineers.com/hemostasis/ innovance-reagents-for-coagulation-disorders
Read more
Tosoh Bioscience introduces SkillPak pre-packed columns
, /in Product News /by 3wmediaGermany-based Tosoh Bioscience has introduced SkillPak 1 mL and 5 mL pre-packed process development columns designed for fast method development and resin screening of monoclonal antibodies, antibody constructs, oligonucleotides, proteins, and viruses.
Tosoh Bioscience, a subsidiary of Tosoh Corporation in Japan, specialises in providing chromatographic solutions for the separation and purification of biomolecules.
Pre-packed with TOYOPEARL®, TSKgel® or Ca++Pure-HA® process chromatography media, SkillPak 1 mL and 5 mL columns deliver high performance and offer scalability and convenience. These columns are ready to use upon receipt and show excellent physical strength and ideal flow characteristics for industrial downstream processing. The pre-packed columns are available with short delivery times in affinity, anion and cation exchange, hydrophobic interaction and size exclusion chromatographic modes. Optimal performance is guaranteed with the columns and they can be operated directly with commonly used low or medium pressure liquid chromatography systems.
SkillPak 1 mL and 5 mL pre-packed columns are available for sale in Europe, Africa and the Middle East.
For more information, visit: https://www.separations. eu.tosohbioscience.com/solutions/process-mediaproducts/ process-development/skillpak
Read more
Awareness Technology releases ChemWell 2, a two-plate ELISA and chemiluminescent analyzer
, /in Product News /by 3wmediaAwareness Technology’s new ChemWell 2 analyzer for ELISA and chemiluminescent (CLIA) is now available.
The ChemWell 2 is a two-probe, two-plate automatic combo analyzer. For 20 years the company has produced single-plate ChemWell automatic ELISA and CLIA systems with the flexibility to run both modes simultaneously even within the same plate. With laboratories expanding serology requirements, the two-plate system is expected to be a more suitable primary instrument for lower throughput labs, and ideal for off-line assays in higher throughput settings.
ChemWell’s flexibility in both hardware and software is key to automating a wide variety of unrelated test methods. Separate probes are used for samples and reagents with an option for disposable tips. Filters range from 405 nm – 630 nm; dispense volume from 2μL to 1.95 ml; plate washing routines, temperature control, and mixing are programmable. Intuitive software offers on-board predilutions, multiple calibration options, replicates, statistics, QC tracking, barcoded sample ID and data management. Additionally, it schedules assays to prevent timing conflicts while providing optimal throughput. An optional laptop stand conserves bench space.
For more information, visit: www.awaretech.com
Read more
Siemens Healthineers releases free eBook on coagulation testing protocols for COVID-19 patients
, /in Corona News, Product News /by 3wmediaSiemens Healthineers has a released an informative eBook titled “Coagulation abnormalities in COVID-19 patients – current testing and treatment protocols” to provide quick access to coagulation testing and treatment recommendations.
The eBook can be downloaded for free from their website: https://bit.ly/2CcpB5I
Because coagulation tests are important in the management of COVID-19 patients, the company has compiled an eBook for quick access to:
The eBook provides an overview of COVID-19 and thrombosis; it looks at laboratory testing in the identification of coagulation abnormalities in COVID-19 patients; and provides information on the treatment of coagulation abnormalities in COVID-19 patients.
Authors of the eBook write that while it’s not unusual for infections to raise the risk of clotting, the COVID-19 virus is associated with an unprecedented range of clotting-related disorders in affected patients. “From benign skin lesions on the feet to life-threatening thrombotic events, the COVID-19 virus has demonstrated a strikingly high prevalence of deadly blood clots. Studies show that about 25% and even up to 70% of critically ill patients have confirmed venous thromboembolism or pulmonary embolism. Another study found that approximately 70% of COVID-19 patients who died had disseminated intravascular coagulation.”
They add that Siemens Healthineers’s coagulation tests play an important role in the diagnosis, treatment, and management of coagulation abnormalities in COVID-19 patients and point out that the company has changed their production model to produce these assays at a higher volume than ever before.
“We are proud to support you in the fight against COVID-19. Behind every healthcare professional there are 53,000 Healthineers,” Siemens Healthineers says.
Read more
Thermo Fisher Scientific introduces new mass spectrometry systems
, /in Product News /by 3wmediaThermo Fisher Scientific has introduced several new products that build on its leading Orbitrap platform and expand research applications. The new Thermo Scientific Orbitrap Exploris 240 mass spectrometer is designed to give scientists working in proteomics, metabolomics, biopharmaceutical characterisation and small-molecules, the analytical performance required for research and high-throughput analyses. The company says the new system will advance discovery and identification with increased accuracy for confident scale-up, while providing operational simplicity and streamlining time-to-result.
Thermo Fisher Scientific pointed out that the new mass spectrometer delivers qualitative and quantitative capabilities synonymous with Orbitrap high-resolution accurate-mass (HRAM) spectrometry, with internal calibration that assures consistent data quality and decision making. These newest systems extend the Thermo Scientific Orbitrap Exploris portfolio of HRAM systems, which were introduced in 2019 with the release of the new-generation Thermo Scientific Orbitrap Exploris 480 mass spectrometer.
Software
Thermo Scientific Proteome Discoverer 2.5 software provides high confidence during peptide identification, accurate quantification and high throughput data analysis for proteomics researchers. Deep learning-based prediction of tandem mass spectra, facilitated through a new collaboration with MSAID, a software company transforming proteomics through deep learning, enables more scientists to benefit from major improvements in identification confidence and reproducibility.
To further enhance characterisation of protein biotherapeutics and oligonucleotide therapeutics, biopharmaceutical laboratories use the Thermo Scientific BioPharma Finder 4.0 software, which provides greater flexibility and customisation for this growing industry.
For small molecule researchers, Thermo Scientific Compound Discoverer 3.2 software further automates unknown compound identification performed on Thermo Scientific Orbitrap Gas Chromatography- Mass Spectrometry (GC-MS) systems to improve productivity.
In addition, the new Thermo Scientific Xcalibur 4.4 software brings the AcquireX intelligent data acquisition workflow to Thermo Scientific Orbitrap Exploris mass spectrometry platform users, enabling the fully automated acquisition of high quality MS/MS data and reducing manual input and repeat runs.
Collaboration
Thermo Fisher Scientific’s collaboration with Evosep, a leading provider of sample preparation technologies for protein-based clinical research, supports the development of high-throughput clinical research workflows for profiling large plasma sample cohorts for proteomics, translational research and pharmaceutical applications. This partnership recently led to the launch of an automated ultra-high throughput plasma protein profiling platform, combing the power of the new Thermo Scientific Orbitrap Exploris 240 mass spectrometer with the Evosep One liquid chromatography solution.
The company’s collaboration with Biognosys, a leading developer of next-generation proteomics solutions, resulted in the development of data-independent acquisition mass spectrometrybased workflows, which enhances sensitivity and coverage for proteomic research in translational and clinical labs. The collaboration includes a novel FAIMS-DIA method that features the Thermo Scientific FAIMS Pro interface, which improves selectivity, reproducibility and proteome coverage, as well as new methods that streamline discovery by combining Thermo Scientific SureQuant Targeted Assay Kits and the Biognosys PQ500 kit in a single workflow.
For more information, visit: www.thermofisher.com
Read more
Shimadzu introduces new HIC-ESP ion chromatograph
, /in Product News /by 3wmediaShimadzu, a leader in analytical instrumentation, has introduced the new HIC-ESP (Ion Chromatograph) featuring a built-in electrodialytic suppressor. This anion suppressor minimizes band spreading and achieves high sensitivity and reliable performance for the quantitative determination of anions.
The suppressor is rugged, providing stable functionality over long periods of operation. The system’s small footprint requires minimal bench space. HIC-ESP covers a wide range of applications in environmental testing, pharma, chemistry and food science.
The HIC-ESP modular inert flow path system integrates a system controller, degasser, pump, CDD detector with temperature-controlled flow cell, autosampler, slim-line oven and the anion suppressor. The system combines a number of special features providing reliable analytical results: Excellent solvent delivery performance, low carryover, fast injection speed (as low as 10 sec), high sample injection precision and repeatability, precise oven temperature regulation and more.
In addition, the ion chromatography system integrates seamlessly with Shimadzu’s LabSolutions platform. This allows users to easily manage parameter setting for IC analysis, batch analyses, autoshutdown, data processing and report creation. Data integrity is assured with the addition of LabSolutions DB and LabSolutions CS.
For more information, visit: www.shimadzu.eu/ liquid-chromatography/nexera/hicesp
Read more
Oxford Immunotec releases T-SPOT Discovery SARS-CoV-2 kit for research into measuring T cell immune response to SARS-CoV-2
, /in Corona News, Product News /by 3wmediaOxford Immunotec Global has released the T-SPOT Discovery SARS-CoV-2 test kit. The kit is for research use only and could make a significant contribution towards development of a new tool to manage the COVID-19 pandemic.
T-SPOT Discovery SARS-CoV-2 builds on Oxford Immunotec’s experience with TB diagnosis and the assessment of immune response to CMV in transplant patients, to apply the Company’s established, proprietary T-SPOT technology to the fight against COVID-19.
While serology is able to detect antibodies to SARS-CoV-2 in the blood of some individuals after infection, little is known about how this confers immunity to COVID-19. T-SPOT technology goes further than simple serology by interrogating the immune system’s T cell response and will enable research into the measurement of the strength of that response to SARS-CoV-2. The strength of this response may be linked to protection from reinfection.
Commenting on the technology, Phill Keefe, Senior Vice President Product Design, Development and Delivery at Oxford Immunotec, said: “Not everyone with COVID-19 infection has detectable antibodies in serology tests, and this may be a bigger problem in the majority who experience only mild or no symptoms. Also, it is not yet clear whether the presence of anti-bodies confers immunity. T cell responses develop before antibody generation and can independently provide protection, so studying T cells could give us new insights into immunity to COVID-19.”
T-SPOT technology is approved in over 60 countries for clinical use to detect TB infection. With over 20 million clinical tests since release, T-SPOT technology:
– Reduces the influence of factors which might affect results, such as other treatments
– Standardises cell numbers in the test to normalise for cell number variations between samples
T-SPOT technology can also be automated using the T-Cell Select reagent kit. Automation solutions are available for low, medium and high throughput settings.
For more information, visit: go.oxfordimmunotec. com/t-spot_discovery_SARS_CoV-2
Read more
Ansh labs launches two new immunoassays for SARS-COV2
, /in Corona News, Product News /by 3wmediaAnsh labs has launched two new immunoassays, SARS-CoV2 IgG and IgM ELISAs, to assist in the fight against the Covid-19 pandemic.
Ansh Labs is releasing these two kits for sale in the United States under the provisions outlined in Section D of Policy for Diagnostic Tests for Coronavirus Disease-2019 during the Public Health Emergency. At the time of going to press, these tests were under review by the FDA for an Emergency Use Authorization.
IgM antibody is the first to be produced in response to viral proteins (antigens) and will be primarily detectable during the early onset of the disease. IgG antibodies are long-lasting and can persist in the bloodstream for many years after infection. This test has the advantage of detecting not only individuals with active infection (IgM), but also those who were previously exposed to the virus and may have subsequently developed immunity (IgG).
Testing for SARS-CoV2 antibodies can help in epidemiological surveillance about the spread of the virus and possible herd immunity. Ansh Labs’ SARS-CoV2 ELISAs are highly accurate with IgG ELISA offering 96% specificity and IgM ELISA offering 99% specificity.
For more information, visit: www.covid-diagnostics.com
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ELITechGroup’s Staining Technology Expands with Aerospray® Cytology Slide Stainer/Cytocentrifuge
, /in Product News /by 3wmediaLogan, UT, January 17, 2020 – ELITechGroup Inc., recognized worldwide as slide staining and cytocentrifuge technologic pioneers and innovators, with nearly 30 patents, over the 35-year lifespan of Aerospray staining technology, announces the launch of the Aerospray Cytology Slide Stainer Cytocentrifuge. The ELITechGroup’s Aerospray Cytology Slide Stainer/Cytocentrifuge automates the preparation and staining of liquid based cytology specimens to facilitate the examination of an array of cell differentiations utilizing Papanicolaou staining techniques. The advantages of the Aerospray Cytology Slide Stainer/Cytocentrifuge is that the device performs two functions of sample preparation through cytocentrifugation and sample staining. The system maximizes cell recovery to the slide through the use of its Cytopro® Rotor, eliminates cross-contamination with an application of fresh stain for each slide, and provides programmable regressive and progressive staining capabilities that can be stored in memory to meet the needs and preferences of any end user. The instrument standardizes staining across multiple labs, provides consistently high-quality control, is low maintenance, reduces the labor/cost per slide, enables laboratory compliance, and is the perfect back-up for high automation laboratories for specialty staining and during maintenance. “ELITechGroup’s portfolio of Aerospray slide stainers and cytocentrifuges has enabled the company to develop a worldwide reputation for performance and reliability. Our new Aerospray Cytology Stainer/Cytocentrifuge proves our commitment to ongoing innovation by expanding into new laboratories where we can offer superior staining results,” says Bryce McEuen, Vice President, Biomedical Systems. ELITechGroup will be showcasing the Aerospray Cytology Slide Stainer/Cytocentrifuge at key industry events throughout the year of 2020. Learn more at AerosprayStaining.com.
About ELITechGroup
ELITechGroup is a privately held group of worldwide manufacturers and distributors of in vitro diagnostic equipment and reagents for clinical systems, microbiology, molecular diagnostics, hematology, cytology, and sweat test systems. Their mission is to improve patient care by empowering laboratories to do more in less time, with accuracy, to enable rapid and accurate course of treatment for patients.
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NovaTec Immundiagnostica’s assays aid diagnosis of SARS-COV-2
, /in Corona News, Product News /by 3wmediaNovaTec provides reliable direct pathogen and antibody detection assays to aid in the diagnosis of SARS-CoV-2. These tests are CE-IVD marked. The development of the assays has been spearheaded by affiliate companies Gold Standard Diagnostics, NovaTec Immundiagnostica, and VIROTECH Diagnostics.
The NovaLisa SARS-CoV-2 (COVID-19) ELISA serological assays feature separate detection of IgG, IgA, and IgM antibodies. These three assays use the nucleocapsid protein (N protein) as antigen for the detection of antibodies to SARS-CoV-2, as it plays an important role in viral pathogenesis, replication and RNA packaging. NovaLisa assays can be automated on several open ELISA systems to provide quick results.
The GSD NovaPrime SARS-CoV-2 is a onestep reverse transcription multiplex Real-Time PCR for the direct detection of SARS-CoV-2. The assay simultaneously detects two target sequences inside the N gene. The multiplex PCR enables a streamlined workflow in one reaction and provides results in approximately 2 hours. An extraction/inhibition control and a positive control are included in the kits. The PCR assay demonstrates excellent performance and no cross-reactivity with common human coronavirus strains.
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