Withaferin A

Scalable synthesis of withanolides: A significant development in cancer research

Researchers at Moffitt Cancer Center have developed a novel method for the scalable synthesis of withanolides, a class of naturally occurring compounds with significant potential in cancer treatment. This groundbreaking approach, published in Science Advances [1], could revolutionise cancer research by providing a reliable and efficient means of producing these vital compounds in large quantities.

Yang Changhuei FPM APIC

Beyond FPM: New imaging technique promises clearer, faster microscopy

A team of engineers at the California Institute of Technology (Caltech) has developed a groundbreaking microscopy method that promises to revolutionise biomedical imaging, digital pathology, and drug screening. The new technique, called Angular Ptychographic Imaging with Closed-form method (APIC), builds upon and surpasses the capabilities of its predecessor, Fourier ptychographic microscopy (FPM).

Cyclosporine 3D

Breakthrough in cyclic peptide synthesis could accelerate antibiotic development

Scientists at King’s College London have developed a rapid method for creating cyclic peptides, potentially accelerating the production of new antibiotics to combat antimicrobial resistance (AMR). The research, published in the Journal of the American Chemical Society [1], demonstrates a technique that reduces synthesis time from hours or days to mere minutes.

Takara Bio Europe Logo

New enzyme promises safer, more cost-effective mRNA synthesis

Takara Bio has unveiled a novel enzyme designed to enhance the safety and efficiency of mRNA production for therapeutic applications. The PrimeCap™ T7 RNA Polymerase (low dsRNA) addresses two significant challenges in mRNA synthesis: reducing immunogenic double-stranded RNA (dsRNA) and lowering the cost of capping.

Gyrolab Anti AAV kit

Gyros Protein Technologies launches innovative kit for detecting anti-AAV antibodies

Gyros Protein Technologies AB has introduced a new kit designed to streamline the detection of pre-existing antibodies against adeno-associated virus (AAV) vectors. The Gyrolab Generic Anti-Adeno Associated Virus (AAV) Kit aims to facilitate qualitative assessment of binding antibodies in both pre-clinical and clinical settings, supporting the development of AAV-based gene therapies.

Indica Labs HALO

Indica Labs releases AI-powered digital pathology software update

Indica Labs, a global leader in AI-powered digital pathology solutions, has announced a significant update to its life sciences software suite. The 4.0 versions of HALO®, HALO AI, and HALO Link offer enhanced capabilities for researchers and pathologists, with a focus on leveraging advanced AI-powered image analysis in an open digital pathology ecosystem.

blood

Novel array promises comprehensive blood typing for clinical research

Thermo Fisher Scientific has introduced a groundbreaking solution for more precise blood genotyping in clinical research. The Applied Biosystems™ Axiom™ BloodGenomiX™ Array and Software offers a single, high-throughput assay capable of detecting most extended and rare blood groups, as well as tissue (HLA) and platelet (HPA) types.

diasorin liaison plex

DiaSorin’s new yeast blood culture assay receives FDA clearance

DiaSorin has announced that its LIAISON PLEX® Yeast Blood Culture (BCY) Assay has received 510(k) clearance from the US Food and Drug Administration (FDA). This marks the second molecular multiplexing panel to be cleared for the company’s LIAISON PLEX® system, following the clearance of the Respiratory Flex Assay in March 2024.

MS

Siemens Healthineers secures CE mark for novel MS blood test

Siemens Healthineers has announced the CE marking of its Neurofilament Light Chain (NfL) assay for multiple sclerosis (MS) management. Developed in collaboration with Novartis Pharma AG, this blood test is designed for use on the Atellica IM Analyzer and the ADVIA Centaur XP/XPT Systems.

Scherm­afbeelding 2024 07 02 om 07.31.06

New quality controls for Group B Streptococcus molecular testing

Bio-Rad Laboratories has expanded its portfolio of molecular quality controls with the introduction of Exact Diagnostics GBS Positive and Negative Run Controls. These new products complement the previously launched Exact Diagnostics GBS Verification & Validation Panel, offering clinical laboratories a comprehensive solution for Group B Streptococcus (GBS) molecular assay quality management.