Nova Biomedical | The Most Clinically Advanced Critical Care Test Menu Now Includes
Creat•eGFR•BUN•ePV•iMg•MCHC
Prime Plus provides the most clinical value of any blood gas/critical care analyzer profile by adding essential tests for kidney function (BUN, Creatinine, eGFR), plasma volume (ePV), ionized magnesium (iMg) and MCHC.
Creatinine, eGFR, and BUN
Over 50% of patients admitted to the ICU develop some degree of acute kidney injury.1 Creatinine, eGFR, and BUN monitoring provides indication of changes in kidney function and helps guide therapy to prevent AKI.
Estimated Plasma Volume (ePV)
The plasma volume status of a patient is one of the top priorities in evaluating and treating critical illness including CHF, ARDS, AKI, and Sepsis.2-4
Ionized Magnesium (iMg)
Hypomagnesemia is a frequent finding in critically ill patients.5 Magnesium therapy guided by real time ionized magnesium monitoring has been shown to improve outcome in these patients.6
Mean Corpuscular Hemoglobin Concentration (MCHC)
Helps differentiate types of anemia.
1. Mandelbaum T et al. Outcome of critically ill patients with acute kidney injury using the AKIN criteria. Crit Care Med 2011;39(12):2659-2664.
2. Kobayashi M et al. Prognostic Value of Estimated Plasma Volume in Heart Failure in Three Cohort Studies; Clin Res Cardiol 2019;108(5): 549-561.
3. Niedermeyer, et al. Calculated Plasma Volume Status Is Associated With Mortality in Acute Respiratory Distress Syndrome. Critical Care Explorations: September 2021, V3(9):1-9.
4. Kim HK et al. Prognostic Value of Estimated Plasma Volume Status in Patients with Sepsis. J Korea Med Sci 2020;9(37):1-10.
5. Soliman HM. Development of ionized hypomagnesemia is associated with higher mortality rates. Crit Care Med 2003;31(4):1082-7.
6. Wilkes NJ et al. Correction of ionized plasma magnesium during cardiopulmonary bypass reduces the risk of postoperative cardiac arrhythmia. Anesth and Analg 2002;95(4) 828-834.