Application of base editors in organoids opens new doors for cancer research
Researchers from the Organoid group (Hubrecht Institute, Utrecht University)) and the Princess Máxima Center (Utrecht, The Netherlands) have taken steps to advance cancer tumour models by using base editors to simultaneously introduce multiple cancer-related mutations into healthy organoids. They thereby succeeded in efficiently making tumour organoids that model liver, colorectal and endometrial cancer. The results […]
