BioSkryb Genomics partnership delivers high- throughput single-cell multiomics workflow
BioSkryb Genomics and Tecan Group have unveiled an integrated single-cell multiomics workflow that promises to transform highthroughput cellular analysis. The partnership combines BioSkryb’s ResolveOME™ Whole Genome and Transcriptome Single-Cell Core Kit in 384-well format with Tecan’s Uno Single Cell Dispenser™, enabling parallel analysis of hundreds to thousands of individual cells whilst significantly reducing manual intervention.
Addressing scalability challenges in single-cell research
The workflow addresses growing demand for scalable multiomics approaches by reducing reliance on time-consuming fluorescence-activated cell sorting (FACS) techniques. By leveraging picoliter-level dispensing accuracy, the integrated system delivers high-quality genomic and transcriptomic sequencing-ready libraries in under ten hours – a considerable improvementover traditional methodologies.
“This workflow brings next-generation single-cell multiomics within reach of every lab,” said Suresh Pisharody, CEO of BioSkryb Genomics. “By reducing the need for complex cell sorting methods like FACS and streamlining the entire multiomic analysis process, researchers can obtain deep genomic and transcriptomic insights with minimal hands-on time.”
Automation enhances reproducibility and throughput
The partnership merges multiomic chemistry with automated precision instrumentation to deliver consistent, high-resolution analysis. Tecan’s contribution focuses on precision dispensing capabilities that integrate seamlessly with BioSkryb’s single-cell protocols, simplifying cell isolation whilst maintaining data quality
“Pairing BioSkryb’s ResolveOME chemistry with the Uno Single Cell Dispenser allows researchers to efficiently scale their single-cell studies whilst maintaining high data quality and reproducibility,” noted Mukta Acharya, Head of Tecan’s Life Sciences business division.
Clinical applications and research implications
The workflow’s emphasis on automation and scalability removes barriers to high-through-put single-cell research, particularly in cancer research, drug development, and precision medicine applications. The integrated approach enables researchers to analyse thousands of single cells in a single experiment, expanding potential for high-resolution biological discovery.
For more information, visit: www.bioskryb.com/resolveome
and www.tecan.com/uno
Digital issue: Please click here for more information
