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Genomic makeup of colorectal cancers predicts immune system ability to fight tumours Colorectal cancers heavily bedecked with tumour-related proteins called neoantigens are likely to be permeated with disease-fighting white blood cells, researchers at Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard report in a new study. Because such an influx of white […]
Most melanomas are driven by mutations that spur out-of-control cell replication, while nevi (moles composed of non-cancerous cells at the skin surface) harbouring the same mutations do not grow wildly. However, changes in the level of gene expression can cause nevi to become melanomas. Dermatologists surmise that 30 to 40 percent of melanomas (approximately 30,000 […]
A new device for studying tumour cells can trap 10,000 individual cells in a single chip. The technique, developed at the University of Michigan, could one day help screen potential cancer treatments based on an individual patient’s tumour and help researchers better understand so-called cancer stem cells. It also sheds light on a controversy: are […]
Distribution of single nucleotide variant (SNV) counts detected through exome sequencing of melanoma samples, grouped by the presence of R alleles of the MC1R locus shown as a boxplot with median, quartiles, whiskers and outliers. For the first time, researchers at the Wellcome Trust Sanger Institute and University of Leeds have proved that gene variants […]
Researchers from Massachusetts Eye and Ear and Schepens Eye Research Institute have shown an association between a defective myogenic response — the regulatory increase or decrease in blood pressure to keep blood flow within the vessels of the retina constant — and early, accelerated development of retinopathy in patients with type 1 diabetes. These findings […]
The latest developments in prenatal technology conceived by scientists at the Wayne State University School of Medicine that make it possible to test for genetic disorders a little more than one month into pregnancy were revealed.In the article, the WSU researchers wrote that their non-invasive testing method – Trophoblast Retrieval and Isolation from the Cervix […]
An international research team has linked rare variations in a cell membrane protein to the wide variation in symptom severity that is a hallmark of porphyria, a rare disorder that often affects the skin, liver and nervous system. St. Jude Children’s Research Hospital helped to lead the research. Porphyrias are a family of diseases usually […]
Sysmex Corporation and Siemens Healthcare Laboratory Diagnostics announced on April 13, 2016 an extension to their long-standing partnership through at least 2020. The contract extension adds a minimum of two additional years to the global supply, distributorship, and sales and service agreement for hemostasis products. The partnership enables laboratory customers around the world to continue […]
Laboratory medicine is one of the major supporting areas of healthcare management. Though representing less than 2% of health expenditure, it affects over 70% of clinical decisions which are taken based on laboratory results and this trend is even growing in the last decade. One of the drivers of this increased significance is a better […]
Not only is breast cancer more than one disease, but a single breast cancer tumour can vary within itself, a finding that University of Pittsburgh Cancer Institute (UPCI) researchers discovered has the potential to lead to very different patient treatment plans depending on the tumour sample and diagnostic testing used. The results demonstrate that tumour […]
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