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Stopping a wound from bleeding is essential for human health. Blood coagulation – in which blood goes from liquid to gel and forms a clot – can prevent excessive bleeding and infection. But exactly what molecular events transpire when blood coagulates has remained somewhat mysterious. Using a new profiling procedure invented by investigators from Brigham […]
It is almost axiomatic in medicine that the study of rare disorders informs the understanding of more common, widespread ailments. Researchers from the Perelman School of Medicine at the University of Pennsylvania who study an inherited disorder of skin, hair follicles, nails, sweat glands, and teeth called hypohidrotic ectodermal dysplasia (HED) have identified a mechanism […]
Lower levels of defective viral RNA molecules can make influenza viruses that affect humans more dangerous. This finding could help to guide patient treatment and provide important information for the design of influenza prevention strategies. Flu viruses have defective genetic material that can activate the infected patient’s immune system, and lower levels of these molecules […]
Gastric carcinoma is one of the most common causes of cancer-related deaths, primarily because most patients present at an advanced stage of the disease. The main cause of this cancer is the bacterium Helicobacter pylori, which chronically infects around half of all humans. However, unlike tumour viruses, bacteria do not deposit transforming genes in their […]
A new study conducted by an international team of lung cancer researchers, including Professor John Field from the University of Liverpool, have identified new genetic variants for lung cancer risk. Lung cancer continues to be the leading cause of cancer mortality worldwide. Although tobacco smoking is the main risk factor, variations in a persons genetic […]
Following the presentation to the European market at EuroMedLab in Athens and to the US market at AACC 2017 of the Thermo Scientific Cascadion SM Clinical Analyser bringing together the ease of use of clinical analysers with the selectivity and sensitivity of liquid chromatography-tandem mass spectrometry (LC-MS/MS), the company will now seek CE marking followed […]
Researchers have developed a more precise way of diagnosing suicide risk, by developing blood tests that work in everybody, as well as more personalized blood tests for different subtypes of suicidality that they have newly identified, and for different psychiatric high-risk groups. The research team, led by scientists at Indiana University School of Medicine, also […]
Researchers have found seven new single-letter changes to DNA that are linked to an increased chance of developing renal cell carcinoma. People with these variants are more likely to develop renal cell carcinoma, through the effect they have on nearby genes. The study team, including researchers from The Institute of Cancer Research, London, have recently […]
Vitamin C may “tell” faulty stem cells in the bone marrow to mature and die normally, instead of multiplying to cause blood cancers. Certain genetic changes are known to reduce the ability of an enzyme called tet methylcytosine dioxygenase 2, or TET2, to encourage stem cells to become mature blood cells, which eventually die, in […]
Heart failure refers to a condition in which heart muscle becomes weakened over time, making it increasingly difficult for the heart to pump blood through the body like it should. It’s a progressive disease that begins when the heart adapts to stressors—high blood pressure, coronary artery disease, or diabetes, for example—in order to work properly. […]
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