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1651

”Superior vena cava (or SVC) – derived atrial fibrillation attributes to both clinical and genetic factors”

Normally, the heart contracts and relaxes to a regular beat. In atrial fibrillation, the upper chambers of the heart beat irregularly, which affects blood flow into the two lower large chambers. This can lead to stroke, heart failure and other heart-related complications. Atrial fibrillation triggers were first identified in the pulmonary veins. Hence, the isolation […]

1652

Biomarkers associated with chronic fatigue syndrome severity

Researchers at the Stanford University School of Medicine have linked chronic fatigue syndrome to variations in 17 immune-system signalling proteins, or cytokines, whose concentrations in the blood correlate with the disease’s severity.The findings provide evidence that inflammation is a powerful driver of this mysterious condition, whose underpinnings have eluded researchers for 35 years.“Chronic fatigue syndrome […]

1653

Glioblastoma ‘ecosystem’ redefined for more effective immunotherapy trials

A research team has revealed the intrinsic gene expression patterns of glioblastoma (GBM) tumours, insights that could drive more effective treatments for GBM, the most common and deadly malignant primary brain tumours in adults. Jackson Laboratory (JAX) Professor Roel Verhaak, Ph.D., is the senior author of a paper showing tumour gene expression patterns distinct from […]

1654

Link between bacterial imbalances and breast cancer

In a newly published study, Cleveland Clinic researchers have uncovered differences in the bacterial composition of breast tissue of healthy women vs. women with breast cancer. The research team has discovered for the first time that healthy breast tissue contains more of the bacterial species Methylobacterium, a finding which could offer a new perspective in […]

1655

Make way for haemoglobin

Every cell in the body, whether skin or muscle or brain, starts out as a generic cell that acquires its unique characteristics after undergoing a process of specialization. Nowhere is this process more dramatic than it is in red blood cells. In order to make as much room as possible for the oxygen-carrying protein haemoglobin, […]

1656

Tourette Syndrome risk increases in people with genetic copy variations

An international team that just conducted the largest study of Tourette Syndrome has identified genetic abnormalities that are the first definitive risk genes for the disorder. Although Tourette has long been thought to have a genetic basis — because the syndrome tends to appear in families — before now no definitive risk genes had been […]

1657

Biosensor could help diagnose illnesses directly in serum

In this age of fast fashion and fast food, people want things immediately. The same holds true when they get sick and want to know what’s wrong. But performing rapid, accurate diagnostics on a serum sample without complex and time-consuming manipulations is a tall order. Now, a team reports that they have developed a biosensor […]

1658

Scientists map mutation that drives tumours in childhood cancer survivors treated with radiation decades later

Neuroscientists have uncovered the genetic basis for why many long-term survivors of childhood cancer develop meningiomas, the most common adult brain tumour, decades after their treatment with cranial radiation. The findings show that radiation causes genetic rearrangements in DNA that result in meningiomas, say co-principal investigators Gelareh Zadeh, neurosurgeon-scientist, Head of Surgical Oncology, and Ken […]

1659

Stago Group acquires HemoSonics LLC

The Stago Group recently announced that it has completed the acquisition of HemoSonics LLC, a company specialized in the development of innovative point-of-care testing solutions based in Charlottesville, VA, with facilities in Durham, NC (USA). With the acquisition of the patented SEER technology (Sonic Estimation of Elasticity via Resonance) and its associated Quantra™ Hemostasis Analyser, […]

1660

1 to 10 mutations are needed to drive cancer, scientists find

For the first time, scientists have provided unbiased estimates of the number of mutations needed for cancers to develop, in a study of more than 7,500 tumours across 29 cancer types. Researchers from the Wellcome Trust Sanger Institute and their collaborators adapted a technique from the field of evolution to confirm that, on average, 1 […]