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Vitamin C may “tell” faulty stem cells in the bone marrow to mature and die normally, instead of multiplying to cause blood cancers. Certain genetic changes are known to reduce the ability of an enzyme called tet methylcytosine dioxygenase 2, or TET2, to encourage stem cells to become mature blood cells, which eventually die, in […]
Heart failure refers to a condition in which heart muscle becomes weakened over time, making it increasingly difficult for the heart to pump blood through the body like it should. It’s a progressive disease that begins when the heart adapts to stressors—high blood pressure, coronary artery disease, or diabetes, for example—in order to work properly. […]
A new diagnostic developed by Alberta scientists will allow men to bypass painful biopsies to test for aggressive prostate cancer. The test incorporates a unique nanotechnology platform to make the diagnostic using only a single drop of blood, and is significantly more accurate than current screening methods. The Extracellular Vesicle Fingerprint Predictive Score (EV-FPS) test […]
Rare variants combined with background genetic risk factors may account for many unexplained cases of familial breast cancer, and knowing the specific genes involved could inform choice of prevention and treatment strategies. Researchers Na Li, MD, Ian Campbell, PhD, lead investigator; and their colleagues at the Peter MacCallum Cancer Centre in Melbourne, Australia, focused their […]
Breast cancer cells that spread to other parts of the body break off and leave the primary tumour at late stages of disease development, scientists from the Wellcome Trust Sanger Institute and their collaborators have found. The results show that catching and treating breast cancer before it spreads is a realistic goal. It also opens […]
A small study by researchers at the National Institutes of Health suggests that mutations in the gene CABLES1 may lead to Cushing syndrome, a rare disorder in which the body overproduces the stress hormone cortisol. The excess cortisol found in Cushing syndrome can result from certain steroid medications or from tumours of the pituitary […]
DiaSys Diagnostic Systems GmbH has established a future-oriented cooperation with Tosoh Bioscience. The aim of this cooperation is to consolidate clinical chemistry (DiaSys BioMajesty® JCA-BM6010/C), immunoassays (Tosoh AIA-CL® 1200), hematology and coagulation analysis either simply with a middleware (EVOLINE® Manager; TOSOH) or fully automated with a track system. The conveyor system (EVOLINE®; Tosoh) offers the […]
A new approach to optical imaging makes it possible to quickly and economically monitor multiple molecular interactions in a large area of living tissue – such as an organ or a small animal; technology that could have applications in medical diagnosis, guided surgery, or pre-clinical drug testing. The method is capable of simultaneously tracking 16 […]
Method to more accurately test anti-cancer drugs have now been developed at the Sahlgrenska Academy, University of Gothenburg. The method paves the way to much earlier assessment of who benefits from a specific drug and who does not. “It is common for cancer patients to be prescribed drugs that fail to help them, often with […]
Adenomatous polyposis coli (APC) is a gene whose mutations are associated with a rare, hereditary form of colorectal cancer known as familial adenomatous polyposis. Research led by scientists at the Institut Pasteur and Inserm have recently demonstrated that mutations to this gene do not only lead to the emergence of colon polyps; they also harm […]
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