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Reporting results, researchers seek ways to develop regenerative therapies for muscle disorders by getting stem cells to fuse and form functioning skeletal muscle tissues. A detour on the road to regenerative medicine for people with muscular disorders is figuring out how to coax muscle stem cells to fuse together and form functioning skeletal muscle tissues. […]
Researchers at the University of Helsinki have found a genetic variation, which associates with the damage caused by maternal alcohol consumption. This genetic variation clarifies the role of genetic factors in the alcohol-induced developmental disorders and could be useful in future diagnostics. The effects of prenatal alcohol exposure (PAE) on placental genes involved in growth […]
An extensive exercise to map genetic variation in Sweden has found 33 million genetic variants, 10 million of which were previously unknown. Large-scale DNA sequencing methods were used to analyse the whole genome of 1,000 individuals from different parts of the country. The study was led by researchers at Uppsala University. “This resource will benefit […]
Couples who are undergoing pre-implantation genetic diagnosis (PGD) in order to avoid transmission of inherited diseases, such as Duchenne muscular dystrophy or cystic fibrosis, should also have their embryos screened for abnormal numbers of chromosomes at the same time, say Italian researchers. By doing this, only embryos that are free not only of the genetic […]
Mologic Ltd, which develops personalized diagnostics, recently announced it has received CE-mark approval for BVPro®, a rapid point-of-care test for patients presenting with symptoms of vaginosis. The company also announced the commercial launch of the test, and that it has signed a 3-year distribution agreement with Hitado GmbH, a leading diagnostic supplier specializing in point-of-care […]
Two types of testicular macrophages have recently been characterized by CNRS researchers at the Marseille-Luminy Immunology Center (CNRS / Inserm / Aix-Marseille University). A novel method of cellular tracing has enabled them to establish the origin, the development and the characteristics of these immune cells. This fundamental discovery is promising to understand some cases of […]
Dr Benjamin Tang and his team have developed a world first test to identify which influenza patients will need urgent, life-saving, medical treatment. The High-risk Influenza Screen Test (HIST) measures ‘an early warning signal’ released by the patient’s body into their blood to ‘kick start’ their immune system’s fight against the infection. The test needs […]
Research by Genevan scientists on gene expression and the non-coding genome is a significant breakthrough for the future of personalized medicine. Geneticists have taken an important step towards true predictive medicine by exploring the links between disease and genetic activity in different tissues. They thus constructed a model, the first step in identifying sequences in […]
Autism spectrum disorder affects approximately one out of every 68 children in the United States. Despite expansive study, the origin and risk factors of the complex condition are not fully understood. To better understand the root causes, an international team led by researchers at OHSU in Portland, Oregon, has applied a new systematic analysis to […]
Researchers led by Arizona State University (ASU) and the Translational Genomics Research Institute (TGen) have identified altered expression of a gene called ANK1, which only recently has been associated with memory robbing Alzheimer’s disease, in specific cells in the brain. Using an extremely precise method of isolating cells called "laser capture microdissection," researchers looked at […]
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