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1761

New Lyme disease tests could offer quicker, more accurate detection

New tests to detect early Lyme disease – which is increasing beyond the summer months –could replace existing tests that often do not clearly identify the infection before health problems occur.In an analysis, scientists from Rutgers University, Harvard University, Yale University, National Institute of Allergy and Infectious Diseases of the NIH and other academic centres, […]

1762

New breast cancer targets

Genome-wide association studies (GWAS) have identified more than 150 genetic variations associated with increased risk for breast cancer. Most of these variants are not located in protein-coding gene regions but are assumed to regulate the expression of certain genes. One way to figure out what these variants are doing is to conduct a cis-eQTL analysis. […]

1764

Single-cell diagnostics for breast cancer

Women diagnosed with breast cancer may benefit from having the molecular subtype of different cells within their tumours identified, argue two researchers. While breast cancer is often treated as a whole, they discuss the growing consensus that cancer cells within a tumour can have multiple origins and respond variably to treatment. The authors advocate for […]

1765

Dozens of new gene changes that point to elevated of prostate cancer risk

As the result of a six-year long research process, Fredrick R. Schumacher, PhD, a cancer epidemiology researcher at Case Western Reserve University School of Medicine, and an international team of more than 100 colleagues have identified 63 new genetic variations that could indicate higher risk of prostate cancer in men of European descent. The findings […]

1766

ELITechGroup and R-Biopharm announce a worldwide agreement

ELITechGroup, a leading company in sample-to-result molecular diagnostics, and R-Biopharm, a globally active life science company, have announced a worldwide agreement to strengthen their positions in molecular infectious disease testing. Under this agreement, R-Biopharm and ELITechGroup will cooperate in the development, production and marketing of Real-Time PCR reagents. “We are very pleased to have won […]

1767

Genetic analysis can improve depression therapy

The failure of drugs such as SSRIs, used to treat depression, can be a result of genetic variations in patients. Variations within the gene that encodes the CYP2C19 enzyme results in extreme differences in the levels of escitalopram achieved in patients. Prescribing the dose of escitalopram based on a patient’s specific genetic constitution would greatly […]

1768

High-sensitivity troponin test reduces risk of future heart attack

A blood test that measures the presence of heart-specific proteins called troponins is used by emergency clinics to diagnose myocardial infarction in patients with chest pain. For the past few years a newer laboratory method has been used at most hospitals in Sweden that is ten times more sensitive than the conventional troponin test. The […]

1769

Pap test fluids used in gene-based screening test for two Gyn cancers

Cervical fluid samples gathered during routine Papanicolaou (Pap) tests are the basis of a new screening test for endometrial and ovarian cancers developed by researchers at the Johns Hopkins Kimmel Cancer Center. PapSEEK detects mutations in DNA that have been identified for specific cancers sooner. Earlier detection of cancer could lead to earlier treatment and […]

1770

EKF procalcitonin assay validated for Beckman AU chemistry analysers

EKF Diagnostics announces that its Stanbio Chemistry Procalcitonin (PCT) LiquiColor® assay has been FDA cleared and validated for use on Beckman AU 480, 680 and 5800 clinical chemistry analysers.  EKF is pleased to confirm the immediate availability of a user-defined application (UDA) for running this 10-minute test for bacterial infection and sepsis on these Beckman […]