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A pioneering study has found that patients with Parkinson’s disease have more errors in the mitochondrial DNA within the brainstem, leading to increased cell death in that area. Experts at Newcastle and Sussex universities also revealed that surviving brain cells in the brainstem have more copies of mitochondrial DNA and this has not been identified […]
A large-scale international study led by the University of Exeter Medical School has discovered new genes linked to parents’ lifespan – which could one day be targeted to help prolong human life. How long we live is determined by a range of factors including our lifestyle and how well we treat factors including blood pressure […]
Two patients with mycosis fungoides (MF) can appear to have identical diseases upon first diagnosis but can have radically different outcomes. MF in an unusual cancer of the T lymphocyte that begins in the skin rather than in the lymph nodes, with the first sign often being a rash. Most patients with MF, the most […]
Research from the University of Liverpool identifies a genetic variant that could improve the safety and effectiveness of corticosteroids, drugs that are used to treat a range of common and rare conditions including asthma, and chronic obstructive pulmonary disease (COPD). Corticosteroids are very effective in the treatment of asthma and COPD, with more than 20 […]
While the microbiome has gained significant attention for its impact on digestive health in recent years, its effect on lung disease has largely remained unstudied. Dr. Patricia Finn says this is a missed opportunity. “The microbiome is the ecosystem of good and bad bacteria living in the body,” said Finn, the Earl M. Bane Professor […]
Beckman Coulter has announced its exclusive sponsorship of the ESCAVO Sepsis Clinical Guide (Sepsis app), a point-of-care medical reference mobile application for healthcare professionals who manage septic patients in acute-care settings. Beckman Coulter’s sponsorship of the Sepsis app ensures this important tool will remain free for all users and that content will continue to be […]
Researchers have identified a type of human leukocyte antigen (HLA) that is associated with the skin disease bullous pemphigoid (BP) in diabetic patients administered with DPP-4 inhibitory drugs.DPP-4 inhibitor (DPP-4i) is widely used to treat type 2 diabetes, but increased cases of bullous pemphigoid (BP) have been reported among patients taking the medicine. BP is […]
New findings from the groundbreaking Trial Assigning Individualized Options for Treatment (Rx), or TAILORx trial, show no benefit from chemotherapy for 70 percent of women with the most common type of breast cancer. The study found that for women with hormone receptor (HR)-positive, HER2-negative, axillary lymph node-negative breast cancer, treatment with chemotherapy and hormone therapy […]
Until very recently, Parkinson’s had been thought a disease that starts in the brain, destroying motion centres and resulting in the tremors and loss of movement. New research shows the most common Parkinson’s gene mutation may change how immune cells react to generic infections like colds, which in turn trigger the inflammatory reaction in the […]
A research team led by National University Health System (NUHS) and Duke-NUS Medical School has used genomic technologies to better understand intestinal metaplasia (IM), a known risk factor for gastric (stomach) cancer. Patients with IM are six times more likely to develop stomach cancer than those without. This study is an important part of an […]
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