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1861

FDA grants Breakthrough Device Designation for Roche’s Elecsys cerebrospinal fluid (CSF) assays to support diagnosis of Alzheimer’s disease

Roche announced in July that the U.S. Food and Drug Administration (FDA) has granted Breakthrough Device Designation to Elecsys® ß-Amyloid (1-42) CSF and Elecsys® Phospho-Tau (181P) CSF. These in vitro diagnostic immunoassays are for the measurement of the ß-Amyloid (1-42) and Phospho-Tau concentrations in cerebrospinal fluid (CSF) in adult patients with cognitive impairment who are […]

1862

Protein content as a marker for response to therapy in brain cancer

Brain tumours vary widely in how they respond to treatment. However, early assessment of therapy response is essential in order to choose the best possible treatment for the patient. Scientists from the German Cancer Research Center (DKFZ) have now been able to show in a study using non-invasive high-resolution 7-Tesla MRI scans that the protein […]

1863

New genetic test improves safety of Inflammatory Bowel Disease treatments

A genetic discovery will make treatment for Crohn’s disease and ulcerative colitis safer, by identifying patients who are at risk of potentially deadly drug side effects. A ground-breaking and large-scale NHS research collaboration, led by the University of Exeter and the Royal Devon & Exeter NHS Foundation Trust, has discovered a gene mutation that allows […]

1864

New toolkit to assess musculoskeletal health in older people

A new way to assess the impact of normal ageing on bones, joints and muscles has been proposed that could provide a benchmark for how well older people are able to keep moving. The composition of the body changes as we get older, as muscle strength and bone density decline. But the challenge to date […]

1865

Tracing the footprints of a tumour: genomic “scars” allow cancer profiling

DNA mutations driving cancer development are caused by different mechanisms, each of them leaving behind specific patterns, or “scars” in the genome. Using CRISPR-Cas9 technology, researchers at CeMM and the Wellcome Trust Sanger Institute at Cambridge, UK were able to show for the first time in cell culture that specific genetic alterations indeed lead to […]

1866

bioLOGICAL – Safety when it matters. Third edition of the Greiner Bio-One customer magazine.

The third edition of the Greiner Bio-One customer magazine bioLOGICAL is now available on the company’s website. The issue presents the Helsingborg-based company Vigmed and its products. The Swedish company was taken over by Greiner Bio-One in 2017. Helpful information about arterial and venous catheters as well as an informative interview about the development and […]

1867

Colorectal cancer screening campaigns can save more than 130,000 lives annually

Digestive Cancers Europe has launched a campaign to promote colorectal cancer screening at the occasion of the start of European Colon Cancer Awareness Month (ECCAM). The event took place at the European Parliament and was hosted by MEP Lieve Wierinck (ALDE). The Basque region, the Netherlands and Slovenia show the way… Building on the successful […]

1868

Special antibodies could lead to HIV vaccine

A small number of people who are infected with HIV-1 produce very special antibodies. These antibodies do not just fight one virus strain, but neutralize almost all known virus strains. Research into developing an HIV vaccine focuses on discovering the factors responsible for the production of such antibodies.A Swiss research team led by the University […]

1869

Thermo Fisher Scientific has announced collaboration to advance noninvasive risk assessments of pregnancy outcomes

Thermo Fisher and NX Prenatal Inc. have entered into a collaboration to develop clinical mass spectrometry-based proteomics assays to monitor fetal health in utero and assess the risk of adverse outcomes, including preterm birth and preeclampsia. This new collaboration recognizes the challenges faced by medical professionals who have few tools available for noninvasive risk stratification […]

1870

Genetic study of epilepsy points to potential new therapies

The largest study of its kind, led by international researchers including scientists at RCSI (Royal College of Surgeons in Ireland), has discovered 11 new genes associated with epilepsy. The research is published in today’s issue of Nature Communications (DOI: 10.1038/s41467-018-07524-z). It greatly advances knowledge of the underlying biological causes of epilepsy and may inform the […]