In a significant move for gene therapy research, Annogen has announced a collaboration with Orchard Therapeutics to identify immune cell-specific human promoters for use in certain pre-clinical hematopoietic stem cell (HSC) gene therapy programmes. This partnership aims to advance the development of more targeted and potentially safer gene therapies for central nervous system (CNS) disorders.
London-based startup Briefly Bio has launched with £1.2 million in pre-seed funding to tackle one of the most pressing issues in scientific research: reproducibility. With an estimated 50% of preclinical research experiments failing to be reproduced, costing the industry over £50 billion annually, Briefly Bio aims to revolutionise how scientists document and share their work.
Leading diagnostics company Beckman Coulter has announced a substantial €10 million investment in its East Clare facility, reinforcing its commitment to innovation and growth in Ireland’s Mid-West region. The investment will significantly enhance the site’s diagnostics production capabilities, with the addition of two new fully automated reagent filling lines and infrastructure upgrades.
Technological partnerships The expansion features Cytiva’s Xcellerex XDR Bioreactor single-use system. Silke Fetzer-Rümpler, Senior Vice President, Commercial at Cytiva, noted the system’s scalability and potential to accelerate clinical and commercial milestones.
Researchers from Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB and partners have developed a groundbreaking approach to identify pathogens in sepsis patients, potentially reducing mortality rates and improving treatment outcomes. The team has been awarded the 2024 Stifterverband Science Prize for their innovative work.
Researchers at Moffitt Cancer Center have developed a novel method for the scalable synthesis of withanolides, a class of naturally occurring compounds with significant potential in cancer treatment. This groundbreaking approach, published in Science Advances [1], could revolutionise cancer research by providing a reliable and efficient means of producing these vital compounds in large quantities.
A team of engineers at the California Institute of Technology (Caltech) has developed a groundbreaking microscopy method that promises to revolutionise biomedical imaging, digital pathology, and drug screening. The new technique, called Angular Ptychographic Imaging with Closed-form method (APIC), builds upon and surpasses the capabilities of its predecessor, Fourier ptychographic microscopy (FPM).
Scientists at King’s College London have developed a rapid method for creating cyclic peptides, potentially accelerating the production of new antibiotics to combat antimicrobial resistance (AMR). The research, published in the Journal of the American Chemical Society [1], demonstrates a technique that reduces synthesis time from hours or days to mere minutes.
UK-based toxicology specialist Contract Research Organisation (CRO) Gentronix has been awarded the prestigious King’s Award for Enterprise for 2024 in recognition of its remarkable international trade performance. The Alderley Park-based firm has demonstrated exceptional growth in overseas earnings, with a 239% increase over the past three years.
UK-based biotechnology firm Nuclera has been awarded two Innovate UK grants totalling £1.14 million to further develop its eProtein Discovery system. The funding comprises a £790,000 flexible, agile, scalable, and sustainable technologies (FASST) grant and a £350,000 Engineering Biology grant.
November 2025
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