Influential ECCMID 2023 sees numerous scientific presentations The 33rd European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) took place in Copenhagen, Denmark, 15-18 April 2023. With around 14,000 professional attendees ECCMID is the largest international meeting of clinical microbiologists and infectious diseases specialists. The event included a comprehensive scientific programme, an industry programme and […]
Faster throughput – together | New streamlined solution for immunosuppressant analysis by LC-MS/MS by Mikaël Levi To face increasing demands on their time and resources, chemical laboratories need easier-to-handle solutions with faster turnaround times, lower costs per sample and full compliance with ever-stricter regulatory standards. Recent work by Alsachim using Shimadzu equipment and software has […]
by Dr Jacqueline Gosink Biomarkers and preanalytics in Alzheimer’s disease Analysis of biomarkers such as amyloid-beta peptides and tau proteins in cerebrospinal fluid (CSF) is nowadays a core criterion in Alzheimer’s disease diagnostics. Test methods such as ELISA and chemiluminescence immunoassay enable robust and reproducible measurement of the analytes in patient CSF samples. Recommendations for […]
by Dr Éva Mészáros Responding to a global health crisis: the evolution of the lab The COVID-19 pandemic forced life sciences laboratories all over the world to suddenly begin high volume PCR testing, to help gain the upper hand over this deadly disease. Many facilities had to adopt new pipetting platforms at short notice to […]
by Professor Stephen Bustin Remodelling qPCR as a tool for molecular diagnostics PCR is an incredibly powerful tool in the field of molecular diagnostics, and its current role is embedded in the clinical laboratory where it is indispensable for non-time-critical routine testing. However, point-of-care testing via lateral flow devices, as seen in the recent […]
‘The Expert Report to the Infected Blood Inquiry: Statistics’ (http://bitly.ws/EAng) found that around 3650 people with bleeding disorders in the UK were infected with HIV or hepatitis viruses through the use of contaminated blood products. In addition, many people (8120) were found to be chronically infected with hepatitis C 10 years or more after receiving […]
Clinical specimens, clinical trial samples and the information associated with them are precious resources that require careful curation. CLI caught up with David Kaye [Vice President and General Manager of BioFortis (a Q2 Solutions company)] to find out more about what this entails.
The investigation of antibodies against pathogenic agents in cerebrospinal fluid (CSF) samples is part of the diagnostic work up in acute or chronic inflammatory processes of the central nervous system. This article describes the analysis of intrathecally produced antibodies in CSF and the interpretation of the results.
What we learned from the last pandemic, which no one saw coming, is that it is difficult to answer the question “How should microbiology laboratories be prepared for the next unknown?” However, the last pandemic also taught us that it is imperative to try to answer such a question. In this article we will try […]
Cushing’s syndrome is related to high production of cortisol and, without timely treatment, it can lead to complications such as heart attacks, strokes and type 2 diabetes. The condition can be diagnosed using a dexamethasone suppression test, which involves tracking the effects of this glucocorticoid medication on cortisol levels. Since the absorption of dexamethasone depends […]
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