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Dementia is one of the leading causes of disability in old age and places a huge burden on society. The growing prevalence of dementia calls for accurate, more accessible biomarkers to facilitate clinical diagnosis and prognosis. Peripheral mediums, such as blood and blood derivates (i.e. plasma and platelets), are currently being investigated for their potential […]
The recent introduction of the CellaVision DC-1 makes it possible for small labs to implement the same digital methodology for performing blood cell differentials that is commonly used by large laboratory organizations. CellaVision recently teamed up with Alberta Public Laboratories (APL) to conduct an in-situ product evaluation assessing the utility and impact of CellaVision DC-1 […]
Urinary kidney injury molecule-1 in renal diseaseMoresco RN, Bochi GV, Stein CS, De Carvalho JAM, Cembranel BM, Bollick YS. Clin Chim Acta 2018; 487: 15–21 Kidney injury molecule-1 (KIM-1), a type l transmembrane glycoprotein, is recognized as a potential biomarker for detection of tubular injury in the main renal diseases. Urinary KIM-1 increases rapidly upon […]
Current measures for diagnosis and therapy of chronic kidney disease are limited. Better biomarkers are required to improve treatment by directing therapeutic intervention, tracking responses to therapy and providing greater understanding of the underlying mechanisms driving renal disease progression. We describe here the development of microRNAs as biomarkers for diabetic kidney disease, the most common […]
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