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Human epidermal growth factor receptor 2 (HER2) in colorectal carcinoma
ERBB2 gene amplification and HER2 protein overexpression occur in 2–5% of colorectal carcinomas and may predict response to targeted anti-HER2 monoclonal antibody therapies in patients with advanced disease. This article discusses the utility of next-generation sequencing and HER2 immunohistochemistry as biomarker assays for optimal selection of patients who may benefit from HER2 inhibitors. by Dr […]
Evaluation of protein induced by vitamin K absence II as a novel tumour marker in pancreatic cancer
Pancreatic cancer is a highly lethal malignancy: as its poor prognosis is also related to a difficulty of early diagnosis, a reliable and easily detectable biomarker is urgently needed. This article aims to describe a new serum tumour marker for pancreatic cancer, protein induced by vitamin K absence II. by Dr Sara Tartaglione, Prof. Antonio […]
CellaVision DC-1
Gonotec – Happy 40th Anniversary!
Gonotec, Berlin, Germany, is celebrating 40 years of manufacturing osmometers and chloridemeters for the pharma/bio, medical and chemical industries. CLI caught up with the current general manager, Jan Celinšek, to discover the company’s story. CLI: How did the company come into existence?Jan Celinšek: In 1979 Klaus Noack and Harald Göritz founded the company Gonotec. They […]